Summary
The Pi phenotypes of 132 individuals of a Bantu population living in Zaire were examined. The MM phenotype was the most common, as in all other populations studied up to now. This paper deals with a new allele, PiL, identified by two-dimensional techniques, and its mode of inheritance is demonstrated. In this small sample, there is a conspicuous absence of PiZ, the allele responsible for such severe diseases as emphysema in adults and cirrhosis in children.
Résumé
Le système Pi a été étudié chez 132 individus d'une population Bantoue du Zaïre. Le phénotype MM est le plus fréquent, comme dans toutes les autres populations étudiées jusqu'àce jour. Un nouvel allèle, PiL est décrit ici, notamment par les techniques bidimensionnelles, et sa transmission est démontrée. Dans ce petit échantillon, l'absence de l'allèle PiZ, responsable d'affections graves (emphysèmes chez l'adulte et cirrhoses chez l'enfant), est à noter.
Zusammenfassung
Die Pi-Typen von 123 Bantu aus Zaire wurden bestimmt. Der Phänotyp MM ist wie bei anderen Populationen der häufigste. Es wird ein neues Allel PiL beschrieben und seine Vererbung nachgewiesen. Das Allel PiZ kommt in der relativ kleinen Population nicht vor.
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This investigation was supported by a grant from the University of rouen, France.
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Vandeville, D., Martin, J.P. & Ropartz, C. α1− Polymorphism of a Bantu population: Description of a mew allele PiL . Hum Genet 21, 33–38 (1974). https://doi.org/10.1007/BF00278562
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DOI: https://doi.org/10.1007/BF00278562