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Human liver alcohol dehydrogenase isoenzyme variations

Improved separation methods using prolonged high voltage starch-gel electrophoresis and isoelectric focusing

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Summary

Human liver alcohol dehydrogenase isozyme patterns were studied using prolonged high voltage starch-gel electrophoresis and gel-slab isoelectric focusing. Homo- and heterodimers of ADH2 locus were easily distinguished from each other. The gene frequencies of ADH 22 and ADH 23 in 46 random liver samples from Germany were found to be 0.044 and 0.424 respectively.

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Authors and Affiliations

  1. Institute of Human Genetics, University of Hamburg, D-2000, Hamburg, Germany

    Shoji Harada, Dharam P. Agarwal & H. Werner Goedde

Authors
  1. Shoji Harada
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  2. Dharam P. Agarwal
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  3. H. Werner Goedde
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Alexander von Humboldt-Foundation Fellow

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Harada, S., Agarwal, D.P. & Goedde, H.W. Human liver alcohol dehydrogenase isoenzyme variations. Hum Genet 40, 215–220 (1978). https://doi.org/10.1007/BF00272304

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  • DOI: https://doi.org/10.1007/BF00272304

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