Summary
Chromosomes from a patient with a satellited Yq were stained with a silver procedure that differentially stains nucleolus organizer regions. The Yqs stained heavily in all cells examined, indicating the presence of ribosomal cistrons at this region. The Yqs also entered into satellite associations with the D and G group chromosomes at a frequency greater than would be expected through chance.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Arrighi, F. E., Hsu, T. C.: Localization of heterochromatin in human chromosomes. Cytogenetics 10, 81–86 (1971)
Bloom, S. E., Goodpasture, C.: An improved technique for selective silver staining of nucleolar organizer regions in human chromosomes. Hum. Genet. 34, 199–206 (1976)
Caspersson, T., Zech, L., Modest, E. J., Foley, G. E., Wagh, U., Simonsson, E.: DNA-binding fluorochromes for the study of the organization of the metaphase nucleus. Exp. Cell Res. 58, 141–152 (1969)
Denton, T. E., Howell, W. M., Barrett, J. V.: Human nucleolar organizer chromosomes: Satellite associations. Chromosoma 55, 81–84 (1976)
Evans, H. J., Buckland, R. A., Pardue, M. L.: Location of the genes coding for 18 and 28 S ribosomal RNA in the human genome. Chromosoma 48, 405–426 (1974)
Genest, P.: An eleven-generation satellited Y chromosome. Lancet 1972 I, 1073
Genest, P., Bouchard, M., Bouchard, J.: A satellited human Y chromosome. Lancet 1967 I, 1279–1280
Goodpasture, C., Bloom, S. E.: Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining. Chromosoma 53, 37–50 (1975)
Goodpasture, C., Bloom, S. E., Hsu, T. C., Arrighi, F. E.: Human Nucleolus organizer: The satellites or the stalks? Am. J. Hum. Genet. 28, 559–566 (1976)
Howard-Peebles, P. N., Stoddard, G. R.: A satellited Yq chromosome associated with trisomy 21 and an inversion of chromosome 9. Hum. Genet. 34, 223–225 (1976)
Howell, W. M.: Visualization of ribosomal gene activity: Silver stains proteins associated with rRNA transcribed from oocyte chromosomes. Chromosoma 62, 361–367 (1977)
Howell, W. M., Denton, T. E., Diamond, J. R.: Differential staining of the satellite regions of human acrocentric chromosomes. Experientia 31, 260–262 (1975)
Miller, D. A., Dev, V. G., Tantravahi, R., Miller, O.J.: Suppression of human nucleolus organizer activity in mouse-human somatic hybrid cells. Exp. Cell Res. 101, 235–243 (1976)
Seabright, M.: A rapid banding technique for human chromosomes. Lancet 1971 II, 971–972
Schmid, W.: Satellites on the long Y chromosome arm: A familial Y/autosomal translocation in man. Cytogenetics 8, 415–426 (1969)
Zankl, H., Bernhardt, S.: Combined silver staining of the nucleolus organizing regions and Giemsa banding in human chromosomes. Hum. Genet. 37, 79–80 (1977)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Howell, W.M., Howard-Peebles, P.N., Block, B.M. et al. Silver stain reveals nucleolus organizer regions on a satellited Yq chromosome. Hum Genet 42, 245–250 (1978). https://doi.org/10.1007/BF00291303
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00291303