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A subpopulation of t(2;14)(p11;q32) cells in ataxia telangiectasia B lymphocytes

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Summary

Partially purified B cells from ataxia telangiectasia (A-T) patients and normal individuals were stimulated with Staphylococcus aureus Cowan I organisms (SAC). High levels of apparently random rearrangements were seen in the A-T B cells only. In addition a t(2;14)(p11;q32) rearrangement was identified in B cells from more than one patient.

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Authors and Affiliations

  1. Cancer Research Campaign Laboratories, Department of Cancer Studies, Medical School, University of Birmingham, B15 2TJ, Birmingham, UK

    S. V. Butterworth & A. M. R. Taylor

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  1. S. V. Butterworth
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  2. A. M. R. Taylor
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Butterworth, S.V., Taylor, A.M.R. A subpopulation of t(2;14)(p11;q32) cells in ataxia telangiectasia B lymphocytes. Hum Genet 73, 346–349 (1986). https://doi.org/10.1007/BF00279098

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  • DOI: https://doi.org/10.1007/BF00279098

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