Summary
Smooth muscle cells of the guinea-pig sphincter pupillae were fixed in the presence of 3% lanthanum nitrate. Although only small amounts of lanthanum were found in plasmalemmal vesicles, large deposits were present within a membrane system resembling sarcoplasmic reticulum. The significance of these findings is discussed in relation to the use of lanthanum nitrate as an extracellular tracer.
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This study was supported by grants from the Australian Research Grants Committee and the National Heart Foundation of Australia. G. R. Campbell is the holder of a Post-Doctoral Fellowship with the National Heart Foundation of Australia. The authors are most grateful to Dr. R. Purves and to Dr. J. Chamley for their constructive criticisms of the manuscript.
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Campbell, G.R., Uehara, Y. & Burnstock, G. Lanthanum nitrate in a smooth muscle membrane system. Z.Zellforsch 147, 157–161 (1974). https://doi.org/10.1007/BF00582790
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DOI: https://doi.org/10.1007/BF00582790