Summary
Using a new albumin prefixation technique, microtubules have been observed in close association with the nuclear pores of neurons and glia. Thus, microtubules may be involved in such phenomena as anchoring, migration or rotation of the nucleus or in chemical messenger transport between nucleus and cytoplasm. Microtubules are also seen running close to the coated pits of dendrites. The implications are discussed.
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The authors gratefully acknowledge the support of grants from the British Medical Research Council (E.G.G.) and USPHS grants NS 09678 and NS 04053; National Institutes of Neurological and Communicative Disorders and Stroke (L.E.W.). We thank Hilary Samson for excellent technical collaboration, Julie Barron and Trevor King for technical assistance and Ann Harris for secretarial help
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Gray, E.G., Westrum, L.E. Microtubules associated with nuclear pore complexes and coated pits in the CNS. Cell Tissue Res. 168, 445–453 (1976). https://doi.org/10.1007/BF00215995
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DOI: https://doi.org/10.1007/BF00215995