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Glial fibrillary acidic protein and differentiation of neonatal rat pituicytes in vitro

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Summary

The appearance and intracellular localisation of glial fibrillary acidic protein (GFAP) in pituicytes in neural lobe cultures of newborn rats aged 7 to 30 days were investigated by use of the indirect immunofluorescence method. GFAP-immunoreactive cells were observed mostly in the outgrowth zone. GFAP was localised in the perikaryal cytoplasm as well as in pituicyte processes. GFAP-positive pituicytes showed considerable morphological polymorphism. The presence of GFAP — astrocytic marker — in pituicytes in vitro and the evident morphological similarity to cultured astrocytes suggest the astroglial character of these cells.

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Weinrander, H., Kowalska, A. Glial fibrillary acidic protein and differentiation of neonatal rat pituicytes in vitro. Cell Tissue Res. 238, 191–195 (1984). https://doi.org/10.1007/BF00215161

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