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Infection with Helicobacter pylori and Leukocyte Response in Patients with Myocardial Infarction

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European Journal of Clinical Microbiology and Infectious Diseases Aims and scope Submit manuscript

Abstract

 To test whether Helicobacter pylori may contribute to the inflammatory response following myocardial infarction, the levels of IgG antibodies to Helicobacter pylori and some parameters of leukocyte activity were measured in 63 patients and 61 comparable controls. Helicobacter pylori-positive patients showed a significantly higher expression of the adhesion molecule LFA-1 on neutrophils than Helicobacter pylori-negative patients (433±29.0 vs. 398.8±38.9 mean fluorescence channels; P<0.0001), whereas no significant difference for any parameters tested was found in control subjects. These data suggest a role of Helicobacter pylori in inducing a leukocyte response following myocardial infarction.

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Authors and Affiliations

  1. Medical Semiology and Methodology, Tor Vergata University (Università Di Roma Tor Vergata) Via di Tor Vergata n 135, 00133, Rome, Italy e-mail: galante@med.uniroma2.it, , , , , , IT

    A. Galante, A. Pietroiusti, S. Carta, L. Franceschelli & P. Piccolo

  2. Institute of Microbiology, University of Messina, , , , , , IT

    A. Mastino

  3. Department of Experimental Medicine and Biochemical Science, Tor Vergata University, Rome, Italy, , , , , , IT

    C. Fontana & S. Grelli

  4. Occupational Medicine, Tor Vergata University, Rome, Italy, , , , , , IT

    A. Bergamaschi & A. Magrini

  5. Department of Experimental Medicine and Biochemical Science, Tor Vergata University, IRCCS S. Lucia, Rome, Italy, , , , , , IT

    C. Favalli

Authors
  1. A. Galante
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  2. A. Pietroiusti
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  3. S. Carta
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  4. L. Franceschelli
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  5. P. Piccolo
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  6. A. Mastino
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  7. C. Fontana
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  8. S. Grelli
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  9. A. Bergamaschi
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  10. A. Magrini
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  11. C. Favalli
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Galante, A., Pietroiusti, A., Carta, S. et al. Infection with Helicobacter pylori and Leukocyte Response in Patients with Myocardial Infarction. EJCMID 19, 298–300 (2000). https://doi.org/10.1007/s100960050479

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  • DOI: https://doi.org/10.1007/s100960050479

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