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Die Absorption von45Ca aus dem Darmtrakt der Ratte

The absorption of45Ca in the intestinal tracts of rats

  • Published:
Zeitschrift für die gesamte experimentelle Medizin einschließlich experimentelle Chirurgie

Summary

This paper describes experiments undertaken to determine the rate of absorption of45Ca from the intestinal tract of rats. The method ofScholer andCode as well asMoll andCode was used.

The rate of absorption during a 60-min-period was for45Ca fastest in the jejunum and decreased towards the aboral end of the intestinal tract. The amount absorbed was largest when a solution with low Ca-concentration was used. An increasing concentration of the cation in the testsolution was followed by a slower rate of absorption. The intestinal uptake followed the equation ofMichaelis Menton in all segments studied.

The influence of K+ ions upon the absorption of Ca++ ions is discussed.

Zusammenfassung

In den vorliegenden Untersuchungen wurde über die Absorption von45Ca aus den verschiedenen Abschnitten des Darmtraktes von Ratten berichtet, die nach der Methode vonScholer u.Code sowieMoll u.Code zur Durchführung kamen. Die Absorptionsgrößen wurden durch Iteration der ansteigenden arteriellen Blutaktivitätskonzentration und der vorher festgestellten Schwundrate errechnet. Die Ergebnisse waren:

  1. 1.

    Die Calciumresorption erfolgte vor allen Dingen im oberen Dünndarmabschnitt und nimmt in aboraler Richtung erheblich ab.

  2. 2.

    Die Ca-ärmere Lösung (Lösung 2, Tabelle) wurde relativ schneller absorbiert als die Ca-reichere Lösung (Lösung 3, Tabelle).

  3. 3.

    Die Beeinflussung verschiedener Ca-Konzentrationen auf die Absorption von45Ca wurde diskutiert, wobei auch auf den Einfluß von K+-Ionen auf den Absorptionsvorgang von Ca++-Ionen eingegangen wurde.

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Authors and Affiliations

  1. II. Medizinische Klinik der Universität München, Deutschland

    H. Moll & P. Sauer

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  1. H. Moll
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  2. P. Sauer
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Herrn Prof. Dr. Dr. G.Bodechtel zum 70. Geburtstag.

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Moll, H., Sauer, P. Die Absorption von45Ca aus dem Darmtrakt der Ratte. Z. Gesamte Exp. Med. 149, 266–276 (1969). https://doi.org/10.1007/BF02044482

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  • DOI: https://doi.org/10.1007/BF02044482

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