Skip to main content
SpringerLink
Log in

Determinants of serum DDT and DDE concentrations

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

Conclusions

  1. 1)

    Measurements of serum DDT concentration are capable of relfecting changes in oral DDT intake accurately and promptly.

  2. 2)

    Serum DDE level is only slightly increased by a 300–600 fold increase in DDT intake over a period of 5 months. It is therefore an essentially worthless measure of recent change in oral DDT intake. Stable individual differences in serum DDE levels, seemingly much wider than differences in dietary patterns (i.e. DDE intake), suggest the importance of individual metabolic factors in determining this level.

  3. 3)

    A high degree of correlation between serum DDT and DDE in day to day samples extracted once by hexane, probably reflects changes in extractability influencing the two measurements similarly.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. DALE, W.E., CURLEY, A. and CUETO, C., JR. Life Sciences5, 47 (1966).

    PubMed  Google Scholar 

  2. FOLCH, J., LEES, M. and STANLEY, G.H. SLOANE, J. Biol. Chem.226, 497 (1957).

    PubMed  Google Scholar 

  3. HAYES, W.J., JR., DURHAM, W.F. and CUETO, C., JR. J.A.M.A.162, 890 (1956).

    Google Scholar 

  4. DURHAM, W.F., ORTEGA, P. and HAYES, W.J., JR. Arch. Int. Pharmacodyn141, 111 (1963).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Entomology, University of Arizona, Tucson, Arizona

    Gail Apple, D. P. Morgan & C. C. Roan

Authors
  1. Gail Apple
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. P. Morgan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. C. Roan
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Apple, G., Morgan, D.P. & Roan, C.C. Determinants of serum DDT and DDE concentrations. Bull. Environ. Contam. Toxicol. 5, 16–23 (1970). https://doi.org/10.1007/BF01545118

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01545118

Keywords

Search

Navigation