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Transport of DDT, DDE, and dieldrin in human blood

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Conclusions

  1. 1.

    Less than 18% of the pp'DDT and pp'DDE found in human blood is carried in the erythrocytes, while dieldrin is distributed between RBC and plasma roughly in proportion to volume.

  2. 2.

    In non-lactescent sera, chylomicra carry less than 1% of the total pesticide. Protein-free serum is virtually devoid of pesticide.

  3. 3.

    pp'DDT and pp'DDE are found in relation to lipoproteins of various densities, but principally in the triglyceride-rich low-density and very-low-density lipoproteins.

  4. 4.

    The plasma albumin, and secondarily the smaller globulins are the principal plasma protein constituents associated with blood-borne pp'DDT and pp'DDE.

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References

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Additional information

From the Department of Entomology, Arizona Agricultural Experiment Station. This research was supported under Contract No. EPA 68-03-0091 of the Pesticide Program, Environmental Protection Agency.

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Morgan, D.P., Roan, C.C. & Paschal, E.H. Transport of DDT, DDE, and dieldrin in human blood. Bull. Environ. Contam. Toxicol. 8, 321–326 (1972). https://doi.org/10.1007/BF01684768

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