References
Kopp JB, Robey PG (1990) Calcif Tiss Int 47:221–229
Farley et al. (1983) Science 222:330–332
Wergedal et al. (1988) Clin Ortho Rel Res 233:274–282
Hall (1987) Bone 8:111–116
Bellows et al. (1990) J Bone Min Res 5:S101-S105
Reed et al. (1990) J Bone Min Res 5:S153
Khokhar, Dandora (1990) Metabolism 39:1118–1121
Ittner et al. (1989) J Bone Min Res 4(Suppl 1):870
Farley JR, Tarbaux N, Hall S, Baylink DJ (1988) Metabolism 37:988–995
Marie PJ, de Vernejoul MC, Lomri A (1990) J Bone Min Res 5:S140
References
Wergedal JE, Lau KHW, Baylink DJ (1988) Fluoride and bovine bone extract influence cell proliferation and phosphatase activities in human bone cell cultures. Clin Oerho Rel Res 233:274–282
Ittner J, Muhleck OS, Kunel EM, Maier P, Puhl W, Pfeiffer EF (1989) Effects of fluoride on osteoporosis-bone derived human osteoblast-like cells. J Bone Min Res 4 (Suppl 1):870
Khokher MA, Dandona P (1990) Fluoride stimulates 3H-thymidine incorporation and alkaline phosphatase production by human osteoblasts. Metabolism 39:1118–1121
Kopp JB, Gehron Robey P (1990) Sodium fluoride does not increase human bone cell proliferation of protein synthesis in vitro. Calcif Tiss Int 47:221–229
Chavassieux P, Valentin-Opran A, Chenu C, Boivin G, Delmas PD, Chapuy MC, Hartmann D, Saez S, Meunier PJ (1987) Long-term effects of sodium fluoride on human osteoblast cultures. In: DV Cohn, TJ Martin, PJ Meunier (eds): Calcium Regulation and Bone Metabolism, vol. 9. Excerpta Medica, Amsterdam, p. 856
Marie PJ, de Vernejoul MC, Lomri A (1990) Fluoride-induced stimulation of bone formation in osteoporosis is associated increased DNA synthesis by osteoblastic cells in vitro. J Bone Min Res 5 (Suppl 1):265
Stein GS, Lina JB, Owen TA (1990) Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J 4:3111–3123
Gehron Robey P, Termine JD (1985) Human bone cells in vitro. Calcif Tiss Int 37:453–460
Hall BK (1987) Sodium fluoride as an initiator of osteogenesis of embryonic mesenchyme in vitro. Bone 8:111–116
Bellows J, Heersche JNM, Aubin JE (1990) The effects of fluoride on osteoblast progenitors in vitro. J Bone Min Res 5 (Suppl 1):S101-S105
Farley JR, Tarbaux NM, Vermeiden JPW, Baylink DJ (1988) In vitro evidence that local and systemic skeletal effectors can regulate 3H-thymidine incorporation in chick calvarial cell cultures and modulate the stimulatory action(s) of embryonic chick bone extract. Calif Tissue Int 42:23–33
Kopp JB, Gehron Robey P (1990) Sodium fluoride lacks mitogenic activity for fetal human bone cells in vitro. J Bone Min Res 5 (Suppl 1):S137-S141
References
Mazess RB (1990) Fracture risk: a role for compact bone. Calcif Tissue Int 47:191–193
Kleerekoper M, Villanueva AR, Stanciu J, Rao DS, Parfitt AM (1985) The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int 37:594–597
Bergot C, Laval-Jeantet A-M, Preteux F, Meunier A (1988) Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis. Calcif Tissue Int 43:143–149
Mosekilde L (1989) Sex differences in age-related loss of vertebral trabecular bone mass and structure—biomechanical consequences. Bone 10:425–432
Parfitt AM (1984) Age-related structural changes in trabecular and cortical bone: cellular mechanism and biomechanical consequences. a) Differences between rapid and slow bone loss. b) Localized bone gain. Calcif Tissue Int 36:S123-S128
References
Kleerekoper M, Villanueva AR, Stanciu J, Sudhaker Roe D, Parfitt AM (1985) The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int 37:594–597
Bonucci E, Ballanti P, Della Rocca C, Milani S, LoCascio V, Imbimbo B (1990) Technical variability of bone histomorphometric measurements. Bone Miner 11:177–186
Podenphant J (1990) Methodological problems in bone histomorphometry and its application in postmenopausal osteoporosis. Danish Med Bull 37:924–433
Wright CDP, Crawley EO, Evans WD, Garrahan NJ, Mellish RWE, Croucher PI, Compston JE (1990) The relationship between spinal trabecular bone mineral content and iliac crest trabecular bone volume. Calcif Tissue Int 46:162–165
Britton JM, Davie MWJ (1990) Mechanical properties of bone from iliac crest and relationship to L5 vertebral bone. Bone 11:21–28
Fazzalari NL, Moore RJ, Manthey BA, Vernon-Roberts B (1989) Comparative study of iliac crest and proximal femur histomorphometry in normal patients. J Clin Pathol 42:745–748
Eventov I, Frisch B, Cohen Z, Hammel I (1991) Osteopenia, hematopoiesis, and bone remodeling in iliac crest and femoral biopsies: a prospective study of 102 cases of femoral neck fractures. Bone 12:1–6
Parfitt AM (1987) Trabecular bone architecture in the pathogenesis and prevention of fracture. Am J Med 82:68–72
Heaney RP (1989) Osteoporotic fracture space: an hypothesis. Bone Miner 6:1–13
Granhed H, Jonson R, Hansson T (1989) Mineral content and strength of lumbar vertebrae. Acta Orthop Scand 60:105–109
Osvalder A-L, Neumann P, Lovsund P, Nordwall A (1990) Ultimate strength of the lumbar spine in flexion: an in vitro study. J Biomechanics 23(5):453–460
Eriksson SA, Isberg BO, Lindgren JU (1989) Prediction of vertebral strength by dual photon absorptiometry and quantitative computed tomography. Calcif Tissue Int 44:243–250
Hansson TH, Roos BO, Nachemson A (1980) The bone mineral content and ultimate compressive strength of lumbar vertebrae. Spine 5:46–55.
Aaron JE, Makins NB, Sagreiya K (1987) The microanatomy of trabecular bone loss in normal aging men and women. Clin Orthop Rel Res 215:260–271
Mazess RB (1982) On aging bone loss. Clin Orthop Rel Res 162:239–252
Jensen KS, Mosekilde Li, Mosekilde Le (1990) A model of vertebral trabecular bone architecture and its mechanical properties. Bone 11:417–423
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Baylink, D.J., Farley, J.R., William Lau, K.H. et al. Sodium fluoride does not increase human bone cell proliferation or protein synthesis in vitro . Calcif Tissue Int 50, 96–97 (1992). https://doi.org/10.1007/BF00297305
Issue Date:
DOI: https://doi.org/10.1007/BF00297305