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Visualization of the liver with99mTc-EHDP in thalassemia major

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Abstract

A case is reported in which substantial liver uptake of99mTc-hydroxyethylidene diphosphonate (99mTc-EHDP) was seen on bone scan. The patient, a 25-year-old male with the diagnosis of thalassemia major made at the age of 3 years, had received regular blood transfusions over many years. Clinical and laboratory evidence of hemosiderosis suggests that the presence of large quantities of iron in the liver of this patient may have been responsible for the hepatic uptake of the bone scanning agent.

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References

  1. Comings DE: Thalassemia. In: Williams WJ Beutler E Erslev AJ Rundles, RW (eds):Hematology pp 328–349. McGraw-Hill Book Company, New York, 1972

    Google Scholar 

  2. Oren VO, Uszler JM: Liver metastases of oat cell carcinoma of lung detected on99mTc-diphosphonate bone scan.Clin Nucl Med 3:355–358, 1978

    PubMed  Google Scholar 

  3. Guiberteau MJ, Potsaid MS, McKusick KA: Accumulation of99mTc-diphosphonate in four patients with hepatic neoplasm.J Nucl Med 17:1060–1061, 1976

    PubMed  Google Scholar 

  4. Lyons KP, Kuperus J, Green HW: Localization of99mTc-pyrophosphate in the liver due to massive liver necrosis.J Nucl Med 18:550–552, 1977

    PubMed  Google Scholar 

  5. Byun HH, Rodman SG, Chung KE: Soft tissue concentration of99mTc-phosphates associated with injections of iron dextran complex.J Nucl Med 17:374–375, 1976

    PubMed  Google Scholar 

  6. Winter PF: Splenic accumulation of99mTc-diphosphonate.J Nucl Med 17:850, 1976

    PubMed  Google Scholar 

  7. Perlmutter S, Jacobstein JG, Kazam E: Splenic uptake of99mTc-diphosphonate in sickle cell disease associated with increased spelnic density on computerized transaxial tomography.Gastrointest Radiol 2:77–79, 1977

    Google Scholar 

  8. Parker JA, Jones AG, Davis MA, Mcllmoyle G, Tow DE: Reduced uptake of bone-seeking Pharmaceuticals related to iron excess.Clin Nucl Med 1:267–268, 1976

    Google Scholar 

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Authors and Affiliations

  1. Division of Nuclear Medicine, Department of Radiology, New York Hospital-Cornell Medical Center, 525 East 68th Street, 10021, New York, NY, USA

    Virgilio A. Valdez & Jerome G. Jacobstein M.D.

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  1. Virgilio A. Valdez
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  2. Jerome G. Jacobstein M.D.
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Valdez, V.A., Jacobstein, J.G. Visualization of the liver with99mTc-EHDP in thalassemia major. Gastrointest Radiol 6, 175–176 (1981). https://doi.org/10.1007/BF01890245

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  • DOI: https://doi.org/10.1007/BF01890245

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