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Lubrication of selected salivary molecules and artificial salivas

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Abstract

The lubrication regime displayed by human salivas (parotid and submandibular-sublingual), purified salivary molecules (the mucins MG1 and MG2 and α-amylases), and selected artificial salivas (Oracare D, Saliva Substitute, and Orthana) was assessed in vitro using a friction-testing device. Thin-film (boundary) lubrication was observed for all of the salivary samples and two of the artificial salivas examined. Oracare D, a glycerol-based artificial saliva, was the exception since it lubricated by a thick-film (hydrodynamic) regime. On a molar basis, the best lubricants of the purified salivary molecules were MG1 > MG2 ≈ nonglycosylated α-amylases ≈ glycosylated α-amylases.

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Authors and Affiliations

  1. Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 109 Foster Hall, 14214, Buffalo, NY, USA

    A. Aguirre D.D.S., M.S., M. S. Reddy Ph.D., F. A. Scannapieco D.M.D., M.S. & M. J. Levine D.D.S., Ph.D.

  2. Department of Physics, State University of New York at Buffalo, Buffalo, New York, USA

    B. Mendoza Ph.D.

  3. Department of Oral Surgery, State University of New York at Buffalo, Buffalo, New York, USA

    M. N. Hatton D.D.S., M.S.

Authors
  1. A. Aguirre D.D.S., M.S.
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  2. B. Mendoza Ph.D.
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  3. M. S. Reddy Ph.D.
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  4. F. A. Scannapieco D.M.D., M.S.
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  5. M. J. Levine D.D.S., Ph.D.
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  6. M. N. Hatton D.D.S., M.S.
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Aguirre, A., Mendoza, B., Reddy, M.S. et al. Lubrication of selected salivary molecules and artificial salivas. Dysphagia 4, 95–100 (1989). https://doi.org/10.1007/BF02407152

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