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The accumulation of11C-methionine in cerebral glioma patients studied with PET

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Summary

Fourteen patients with cerebral gliomas were studied with positron emission tomography (PET) using L-[methyl-11C]methionine (11C-MET). Positive images of tumour were obtained in all cases regardless of histological grades. The analysis of differential absorption ratio (DAR) showed the higher accumulation of11C-MET in high grade gliomas than in low grade gliomas. PET study with11C-MET will be of great value not only in delineating the location of gliomas, but also in making a qualitative diagnosis from the view point of the biological properties of gliomas.

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Authors and Affiliations

  1. Division of Neurosurgery, Institute of Brain Diseases, Tohoku University School of Medicine, Sendai, Japan

    M. Kameyama, R. Shirane, J. Itoh, K. Sato, R. Katakura & T. Yoshimoto

  2. Division of Nuclear Medicine, Tohoku University, Sendai, Japan

    J. Hatazawa & M. Itoh

  3. Division of Radiopharmaceutical Chemistry, Cyclotron RI Center, Tohoku University, Sendai, Japan

    T. Ido

Authors
  1. M. Kameyama
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  2. R. Shirane
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  3. J. Itoh
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  4. K. Sato
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  5. R. Katakura
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  6. T. Yoshimoto
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  7. J. Hatazawa
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  8. M. Itoh
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  9. T. Ido
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Kameyama, M., Shirane, R., Itoh, J. et al. The accumulation of11C-methionine in cerebral glioma patients studied with PET. Acta neurochir 104, 8–12 (1990). https://doi.org/10.1007/BF01842885

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  • DOI: https://doi.org/10.1007/BF01842885

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