Summary
The authors report their experience with 150 cases of discectomies performed with interbody grafts using a copolymer (Biocompatible Orthopedic Polymer or BOP*). Made of N-Vinylpyrrolidone-Methylmethacrylate monomers, polyamide fibres and calcium gluconate. BOP is a biocompatible, biodegradable, osteoconductive matrix, easy to use and quite safe. These properties are quite well appreciated for cervical interbody grafting. After discectomy, stabilization of the spine is immediate, and fusion slowly occurs around and through the biopolymer within one year. The biomaterial avoids morbidity inherent in the harvesting of an autograft, as well as any limitations resulting from the use of allografts.
Similar content being viewed by others
References
Albee FH (1923) Fundamentals in bone transplantation. Experiences in three thousand bone graft operations. JAMA 81: 1429
Bailey RW, Badgley CE (1960) Stabilization of the cervical spine by anterior fusion. J Bone Jt Surg 42-A: 565–694
Barron DW (1980) Pulmonary embolic syndrome caused by cementing of hip endoprosthesis. Acta Orthop Scand 51: 921–923
Bechtel A, Willert HG, Frech HA (1973) Bestimmung des Monomergehaltes von Methacrylsäure-methylester in Knochenmark, Fett und Blut nach Aushärten verschiedener „Knochenzemente“. Chromatographia 6: 226–228
Bunn CW (1953) Fibers from synthetic polymers. R Hill (ed), Elsevier, Amsterdam
Burwell RG, Gowland G, Dexter F (1963) Studies in the transplantation of bone. VI. Further observations concerning the antigenicity of homologous cortical and cancellous bone. J Bone Jt Surg 3, 45-B: 597–608
Cameron HV, Mac Nab I, Pilliar RM (1977) Evaluation of a biodegradable ceramic. J Biomed Mat Res 11: 179
Chollet MC, Skondia V, Degraeve N (1986) Evaluation of the mutagenic potential of a co-polymer of N-Vinylpyrrolidone and methylmetacrylate reinforced with polyamide fibers. XVIth Annual Meeting of the European Environment Mutagen Society, Brussels
Christel P, Chabot F, Leray JL, Morin C, Vert M (1982) Biodegradable composites for internal fixation. Biomaterials 80. Wiley & Sons Ltd, London, p 271
Cloward RB (1963) Lesions of the intervertebral discs and their treatment by interbody fusion method. Clin Orthop 27: 51–75
Forster IW, Ralis ZA, Mc Kibbin B, Jenkins DHR (1978) Biological reaction to carbon fiber implants. Clin Orthop 131: 299–307
Friedlander G (1982) Current concepts review bone-banking. J Bone Jt Surg 64-A: 307–311
Hollinger JO (1983) Preliminary report on the osteogenic potential of a biodegradable copolymer of polyactide (PLA) and polyglycolide (PGA). J Biomed Mat Res 17: 71
Holmes RE (1979) Bone regeneration within a coralline hydroxyapatite implant. Plast Reconstr Surg 63
Hulliger L (1962) Untersuchungen über die Wirkung von Kunstharzen (Palacos und Ostamer) in Gewebekulturen. Arch Orthop Unfall-Chir 54: 581–588
Jackson JW (1971) Surgical approaches to the anterior aspect of the spinal column. Ann R Coll Surg Engl 48: 83–98
Kaufman HS (1977) Introduction to polymer science and technology. John Wiley & Sons, New York, p 92
Kronenthal RL (1975) Polymers in medicine and surgery. Biodegradable polymers in medicine. Polym Sci Tech 8: 119
Mankin HJ, Dopplelt S, Tomford W (1983) Clinical experience with allograft implantation. Clin Orthop 174: 69–86
Mc Murray GN (1982) The evaluation of Kiel bone in spinal fusions. J Bone Jt Surg 64-B: 101–104
Merendino J, Sertl G, Skondia V (1984) Use of biocompatible orthopaedic polymer for fracture treatment and reconstructive orthopaedic procedures. J Int Med Res 12: 351–355
Oppenheimer BS, Oppenheimer ET, Danishefsky I, Stout AP, Eirich FR (1955) Further studies of polymers as carcinogenic agents in animals. Cancer Res 15: 333–340
Oppenheimer BS, Oppenheimer ET, Stout AP, Wilhite M, Danishefsky I (1958) The latent period in carcinogenesis by plastics in rats and its relation to the presarcomatous stage. Cancer 11: 204–213
Petty W (1978) The effect of methylmetacrylate on chemotaxis of polymorphonuclear leukocytes. J Bone Jt Surg 60-A: 492–498
Petty W (1978) The effect of methylmetacrylate on bacterial phagocytosis and killing by human polymorphonuclear leukocytes. J Bone Jt Surg 60-A: 752–757
Petty W, Spannier S, Shuster JJ (1985) The influence of skeletal implants on incidence of infection. Experiments in a canine model. J Bone Jt Surg 67-A: 1236–1244
Ramani PS, Kalbag RM, Sengupta RP (1975) Cervical spinal interbody fusion with Kiel bone. Br J Surg 62: 147–150
Skondia V, Davydov AB, Belykh SI, Heusghem C (1987) Chemical and physico-mechanical aspects of biocompatible orthopaedic polymer (BOP) in bone surgery. J Int Med Res 15, 5: 293–302
Smith GW, Robinson RA (1958) The treatment of certain cervical spinal disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Jt Surg (Am) 40-A: 607–624
Taheri ZE (1972) Experience with calf bone in cervical interbody spinal fusion. J Neurosurg 36: 67–71
Tomford WW, Dopelt S, Mankin HJ (1983) 1983 Bone Bank Procedus. Clin Orthop Rel Res 174: 15–21
Author information
Authors and Affiliations
Additional information
DTA s.a., 217, rue Royale, B-1030, Bruxelles, Belgique; 175 South Main Street, Suite 560, Salt Lake City, UT84111, U.S.A.; ICP France, B.P.91, F-52003 Chaumont Cédex, France.
Rights and permissions
About this article
Cite this article
Lozes, G., Fawaz, A., Cama, A. et al. Discectomies of the lower cervical spine using interbody biopolymer (B.O.P.) implants. Acta neurochir 96, 88–93 (1989). https://doi.org/10.1007/BF01456164
Issue Date:
DOI: https://doi.org/10.1007/BF01456164