Summary
The strains of H1N4 influenza A virus isolated from feral ducks in Japan in 1977–78 were compared to swine-origin H1N1 viruses antigenically and genetically. Homologous characteristics were found among the H1N4 isolates from feral ducks in hemagglutination-inhibition (HI) tests, viral RNA patterns on polyacrylamide gel electrophoresis and oligonucleotide mapping. Although the hemagglutinins of duck-origin viruses employed in this study were identified as H1, the viruses were distinguishable from A/New Jersey/8/76 (H1N1), A/duck/Alberta/35/76 (H1N1) and the virus isolated from swine in Japan in the cross HI test. Also, the viral RNA patterns of the duck- and swine-origin H1 viruses were found to be quite different, indicating that genetic reassortment of HA genes between them is unlikely. After H1N4 virus of duck-origin was intranasally inoculated into pigs, a brief period of virus recovery with no serological response was observed; whereas swine-origin H1N1 virus produced seroconversion in the pigs inoculated.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Butterfield, W. K., Campbell, C. H., Webster, R. G., Shortridge, K. F.: Identification of a swine influenza virus (Hsw 1 N 1) isolated from a duck in Hong Kong. J. Inf. Dis.138, 686–689 (1978).
Hinshaw, V. S., Webster, R. G., Turner, B.: Novel influenza A viruses isolated from Canadian feral ducks: Including strains antigenically related to swine influenza (Hsw 1 N 1) viruses. J. gen. Virol.41, 115–127 (1978).
Hinshaw, V. S., Bean, W. J. Jr., Webster, R. G., Easterday, B. C.: The prevalence of influenza viruses in swine and the antigenic and genetic relatedness of influenza viruses from man and swine. Virology84, 51–62 (1978).
Hinshaw, V. S., Webster, R. G., Rodriguez, R. J.: Influenza A virus: Combination of hemagglutinin and neuraminidase subtypes isolated from animals and other sources. Brief review. Arch. Virol.67, 191–201 (1981).
Kendal, A. P., Noble, G. R., Dowdle, W. R.: Swine influenza viruses isolated in 1976 from man and pig contain two coexisting subpopulations with antigenically distinguishable hemagglutinins. Virology82, 111–121 (1977).
Kida, H., Yanagawa, R., Matsuoka, Y.: Duck influenza lacking evidence of disease signs and immune response. Infect. Immun.30, 547–553 (1980).
Morbidity and Mortality Weekly Report: U.S. Department of Health, Education and Welfare,25, 47–48 (1976).
Nakajima, K., Desselberger, U., Palese, P.: Recent human influenza A (H 1 N 1) viruses are closely related genetically to strains isolated in 1950. Nature274, 334–339 (1978).
Ottis, K., Bachman, P. A.: Occurrence of Hsw 1 N 1 subtype influenza A viruses in wild ducks in Europe. Arch. Virol.63, 185–190 (1980).
Palese, P., Schulman, J. L.: Difference in RNA patterns of influenza A viruses. J. Virol.17, 876–884 (1976).
Palmer, D. F., Coleman, M. T., Dowdle, W. R., Schild, G. C. (eds.), Centers for Disease Control: Advanced Laboratory Techniques for Influenza Diagnosis. U.S. Department of Health, Education and Welfare, Immunology Series No. 6, Atlanta (1975).
Smith, T. F., Burgert, E. O. Jr., Dowdle, W. R., Noble, G. R., Campbell, R. J., Scoy, R. E. Van.: Isolation of swine influenza virus from autopsy lung tissues of man. New Engl. J. Med.294, 708–710 (1976).
Stuart-Harris, C. H., Schild, G. C.: Influenza viruses of lower animals and birds. In: Influenza, the Viruses and the Disease, 78–95. London: Edward Arnold Ltd. 1976.
Sugimura, T., Ogawa, T., Tanaka, Y., Nishimori, K.: An epidemic of swine influenza in Japan. Res. Vet. Sci.31, 407–415 (1981).
Yamane, N., Sukeno, N., Ishida, N.: Distribution of swine influenza antibody in Japan. Tohoku J. exp. Med.125, 325–330 (1978).
Yamane, N., Odagiri, T., Arikawa, J., Morita, M., Sukeno, N., Ishida, N.: Isolation of orthomyxoviruses from migrating and domestic ducks in northern Japan in 1976–1977. Jpn. J. Med. Sci. Biol.31, 407–415 (1978).
Yamane, N., Arikawa, J., Odagiri, T., Ishida, N.: Annual examination of influenza virus infection among pigs in Miyagi Prefecture, Japan. The appearance of Hsw 1 N 1 virus. Acta Virol.23, 240–248 (1979).
Yamane, N., Odagiri, T., Arikawa, J., Ishida, N.: Isolation and characterization of influenza A viruses from wild ducks in northern Japan. Appearance of Hsw 1 antigens in Japanese duck population. Acta Virol.23, 375–384 (1979).
Yoden, S., Kida, H., Yanagawa, R.: An avian influenza virus of which infectivity is neutralized by antisera lacking hemagglutination-inhibition activity. Arch. Virol.74, 205–210 (1982).
Author information
Authors and Affiliations
Additional information
With 3 Figures
Rights and permissions
About this article
Cite this article
Arikawa, J., Yamane, N., Totsukawa, K. et al. Antigenic and genetic characterization of H1 influenza viruses isolated from feral ducks and swine in Japan. Archives of Virology 78, 19–27 (1983). https://doi.org/10.1007/BF01310855
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01310855