Skip to main content
SpringerLink
Log in

Wirkung von Milchbestandteilen auf den Lipidstoffwechsel

  • Originalarbeiten
  • Published:
Zeitschrift für Ernährungswissenschaft Aims and scope Submit manuscript

Zusammenfassung

In sechs Versuchen mit wachsenden Schweinen wurden verschiedene Milchbestandteile auf ihre cholesterinsenkende Wirkung untersucht. Die Versuche werden einzeln beschrieben.

Mit Hilfe der Hauptkomponenten-Analyse wurden anschließend 44 Faktoren geprüft, ob sie den Lipidstoffwechsel beeinflussen. Dabei zeigte sich, daß nicht ein bestimmter Inhaltsstoff der Milch eine cholesterinsenkende Wirkung hat. Milch und Milchbestandteile verändern die Nährstoffzusammensetzung der Nahrung und können indirekt, z. B. über das veränderte Aminosäuremuster den Lipidgehalt des Blutes senken.

Summary

The cholesterol lowering effect of various milk constituents was examined in six trials with growing pigs. Each trial is described.

By means of main component analysis 44 factors were tested in order to see whether they influenced the lipid metabolism. We observed that there was no specific component in the milk which showed a cholesterol lowering effect. Milk and milk constituents change the nutrient composition of the food and can, e.g. by means of the changed amino acid pattern, indirectly lower the lipid content in the blood.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Antila M, Ali-Yrkkö S, Antila V, Antila P, Rönnemaa T, Järveläinen H, Viikari J (1980) Is fat globule membrane essential for cholesterol-lowering effect of milk? Lancet 602

  2. Autorengruppe Nationales Forschungsprogramm 1 (1982) Prophylaxe von Herz-Kreislauf-Krankheiten in der Schweiz. Haupt, Bern/Stuttgart

    Google Scholar 

  3. Barth CA, Pfeuffer M, Hahn G (1984) Influence of dietary casein or soy protein on serum lipids and lipoproteins of monkeys. Ann Nutr Metab 28:137–143

    Article  CAS  Google Scholar 

  4. Beynen AC, Scholz KE, Zutphen van LFM, West CE (1983) Correlation between the colesterolemic responses produced by dietary cholesterol and casein in rabbits. J Nutr 113:1204–1211

    CAS  Google Scholar 

  5. Beynen AC, West CE (1981) The distribution of cholesterol between lipoprotein fractions of serum from rabbits fed semipurified diets containing casein and either coconut oil or corn oil. Z Tierphysiol, Tierernährg u. Futtermittelkde 46:233–239

    Article  CAS  Google Scholar 

  6. Bruppacher R (1977) Zur Ernährungslage der Adoleszenten. In: Brubacher G, Ritzel G (Hrsg), Zur Ernährungssituation der schweizerischen Bevölkerung. Huber, Bern/Stuttgart/Wien

    Google Scholar 

  7. Chapman MJ, Goldstein S (1976) Comparison of the serum low density lipoprotein and of its apoprotein in the pig, rhesus monkey and baboon with the man. Atherosclerosis 25:267–291

    Article  CAS  Google Scholar 

  8. Gibney MJ (1983) The effect of dietary lysine to arginine ratio on cholesterol kinetics in rabbits. Atherosclerosis 47:263–270

    Article  CAS  Google Scholar 

  9. Grunewald KK (1982) Serum cholesterol levels in rats fed skim milk fermented by Lactobacillus acidophilus. J Food Sci 47:2078–2079

    Article  CAS  Google Scholar 

  10. Helms P (1977) Hypocholesterolaemic effect of milk. Lancet: 556

  11. Hepner G, Fried R, St. Jeor S, Fusetti L, Morin R (1979) Hypocholesterolemic effect of yogurt and milk. Am J Clin Nutr 32:19–24

    CAS  Google Scholar 

  12. Howard AN, Marks J (1977) Hypocholesterolaemic effect of milk. Lancet: 255–256

  13. Hussi E, Miettinen TA, Ollus A, Kostiainen E, Ehnholm C, Haglund B, Huttunen JK, Manninen V (1981) Lack of serum cholesterol-lowering effect of skimmed milk and butter milk under controlled conditions. Atherosclerosis 39:267–272

    Article  CAS  Google Scholar 

  14. Kim DN, Lee KT, Reiner JM, Thomas WA (1980) Increased steroid excretion in swine fed high fat, high cholesterol diet with soy protein. Exp Mol Path 33:25–35

    Article  CAS  Google Scholar 

  15. Kim DN, Lee KT, Reiner JM, Thomas WA (1982) Hypolipidemic action of soy protein in swine. In: Noseda G, Fragiacomo C, Fumagalli R, Paoletti R (Eds), lipoproteins and coronary atherosclerosis. Elsevier Biomedical Press

  16. Knipping GMJ, Kostner GM, Holasek A (1975) Studies on the composition of pig serum lipoproteins, isolation and characterization of different apoproteins. Biochim Biophys Acta 393:88–99

    Article  CAS  Google Scholar 

  17. Kritchevsky D, Tepper SA, Morrissey RB, Czarnecki SK, Klurfeld DM (1979) Influence of whole or skim milk on cholesterol metabolism in rats. Am J Clin Nutr 32:597–600

    CAS  Google Scholar 

  18. Mahley RW, Weisgraber KH, Innerarity T, Brewer HB, Assmann G (1975) Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding. Biochemistry 14:2817–2823

    Article  CAS  Google Scholar 

  19. Malinow MR, McLaughlin P (1975) The effect of skim milk on plasma cholesterol in rats. Experientia 31:1012–1013

    Article  CAS  Google Scholar 

  20. Mann GV (1977) Hypocholesterolaemic effect of milk. Lancet: 556

  21. Mann GV (1977) A factor in yogurt which lowers cholesteremia in man. Atherosclerosis 26:335–340

    Article  CAS  Google Scholar 

  22. Mann GV, Shaffer RD, Anderson RS, Sandstead HH (1964) Cardiovascular disease in the Massai. J. Atheroscler Res 4:289–312

    Article  CAS  Google Scholar 

  23. Mann GV, Spoerry A (1974) Studies of a surfactant and cholesteremia in the Massai. Am J Clin Nutr 27:464–469

    CAS  Google Scholar 

  24. Mardia KV, Kent JT, Bibby JM (1979) Multivariate analysis. Academic Press, London/New York, pp 213–237

    Google Scholar 

  25. Marks J, Howard AN (1977) Hypocholesterolaemic effect of milk. Lancet: 763

  26. Nagata Y, Imaizumi K, Sugano M (1980) Effects of soya-bean protein and casein on serum cholesterol levels in rats. Br J Nutr 44:113–121

    Article  CAS  Google Scholar 

  27. Nagata Y, Tanaka K, Sugano M (1981) Further studies on the hypocholesterolaemic effect of soya-bean protein in rats. Br J Nutr 45:233–241

    Article  CAS  Google Scholar 

  28. Nair CR, Mann GV (1977) A factor in milk which influences cholesteremia in rats. Atherosclerosis 26:363–367

    Article  CAS  Google Scholar 

  29. Noseda G, Fragiacomo C (1980) Effects of soybean protein diet in serum lipids, plasma glucagon and insulin. In: Noseda G, Leweis B, Paoletti R (Eds) Diet and drugs on atherosclerosis. Raven Press, New York, pp 61–65

    Google Scholar 

  30. Raaij van JMA, Katan MB, Hautvast JGA (1979) Casein, soya protein, serum-cholesterol. Lancet: 958

  31. Ratcliffe HL, Luginbühl H (1971) The domestic pig: a model for experimental atherosclerosis. Atherosclerosis 13:133–136

    Article  CAS  Google Scholar 

  32. Richardson T (1978) The hypocholesteremic effect of milk — a review. J Food Protection 41:226–235

    Article  CAS  Google Scholar 

  33. Ritzel G (1975) Evaluation von Ernährungserhebungen im Rahmen der Basler Studie III. In: Brubacher G, Ritzel G (Hrsg) Zur Ernährungssituation der schweizerischen Bevölkerung. Huber, Bern/Stuttgart/Wien, S 57–82

    Google Scholar 

  34. Ritzel G, Stähelin HB, Schneeberger H, Wanner M, Jost M (1979) Serum lipids in swine fed large quantities of whey. Int J Vit Nutr Res 49:419–427

    CAS  Google Scholar 

  35. Rossouw JE, Burger EM, Vyver van der P, Ferreira JJ (1981) The effect of skim milk, yogurt and full cream milk on human serum lipids. Am J Clin Nutr 34:351–356

    CAS  Google Scholar 

  36. Sautier C, Dieng K, Flament C, Doucet C, Suquet JP, Lemonnier D (1983) Effects of whey protein, casein, soya-bean and sunflower proteins on the serum, tissue and faecal steroids in rats. Br JNutr 49:313–319

    Article  CAS  Google Scholar 

  37. Sirtori CR, Agradi E, Conti F, Mantero O, Gatti E (1977) Soyabean protein diet in the treatment of type II hyperlipoproteinemia. Lancet: 275–277

  38. Terpestra AHM, Tintelen van G, West CE (1982). The effect of semipurified diets containing different proportions of either casein or soybean protein on the concentration of cholesterol in whole serum, serum lipoproteins and liver in male and female rats. Atherosclerosis 42:85–95

    Article  Google Scholar 

  39. Thakur CP, Jha AN (1981) Influence of milk, yogurt and calcium on cholesterol-induced atherosclerosis in rabbits. Atherosclerosis 39:211–215

    Article  CAS  Google Scholar 

  40. The pooling project research group (1978) Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: final report of the pooling project. J Chron Dis 31:301

    Google Scholar 

  41. West CE, Deuring K, Schutte JB, Terpestra AHM (1982) The effect of age on the development of hypercholesterolemia in rabbits fed semipurified diets containing casein. J Nutr 112:1287–1295

    CAS  Google Scholar 

  42. Wissler RW (1980) Principles of the pathogenesis of atherosclerosis in ‘heart disease’. In: Braunwald E (Ed) Saunders Philadelphia p 1221

    Google Scholar 

  43. Wostmann BS, Bruckner-Kardoss E (1980) The effect of long-term feeding of 10% dietary lactose on serum, liver and aortic cholesterol of the rat and the gerbil. J Nutr 110:82–89

    CAS  Google Scholar 

Download references

Author information

Author notes

  1. G. Ritzel

    Present address: Abteilung für Sozial- und Präventiv-Medizin, Universität Basel, Schweiz

Authors and Affiliations

  1. Eidg. Forschungsanstalt für viehwirtschaftliche Produktion, Posieux, Schweiz

    M. Wanner, P. Stoll, H. Schneeberger, M. Jost & J. Danuser

  2. Geriatrische Klinik, Kantonsspital, Basel, Schweiz

    H. Stähelin

Authors
  1. M. Wanner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Stoll
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Stähelin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. Schneeberger
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Jost
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Danuser
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. G. Ritzel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wanner, M., Stoll, P., Stähelin, H. et al. Wirkung von Milchbestandteilen auf den Lipidstoffwechsel. Z Ernährungswiss 24, 141–157 (1985). https://doi.org/10.1007/BF02019353

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02019353

Schlüsselwörter

Search

Navigation