Summary
The retention behaviour of aromatic acids was examined in a reversed-phase mode liquid chromatography. Macro porous styrene-divinylbenzene copolymers were selected on the basis of their chemical stability throughout the entire pH range.
The effect of addition of a hydrophobic ion in the eluent and that of an ion-exchange group on the packing were discussed in relation with the hydrophobicity and the dissociation constant of solutes.
The maximum capacity ratios of the acids on apolystyrene gel are linearly related with the hydrophobicity. The prediction of the retention time of aromatic acids could be possible by combination of their hydrophobicity and their dissociation constants.
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Hanai, T., Hubert, J. Chromatographic behaviour of acids on macro-porous-polystyrene gels. Chromatographia 17, 633–639 (1983). https://doi.org/10.1007/BF02261948
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DOI: https://doi.org/10.1007/BF02261948