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Performance of open tubular columns as a function of tube diameter and liquid phase film thickness

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Summary

Wall-coated, open-tubular (capillary) columns prepared from different diameter tubing, with different liquid phase film thickness, are compared with each other and with packed and support-coated open-tubular columns. The comparison is based on the variation of the phase ratio and the capacity factor, and includes column efficiency (HETP, theoretical plate number), resolution, retention time, and sample capacity. Problems associated with the evaluation of the sample capacity are outlined. The influence of temperature on column performance is discussed in detail. Finally, the possibilities of short, wide-bore open-tubular columns prepared with a thick liquid-phase film are demonstrated.

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References

  1. L. S. Ettre, E. W. March, J. Chromatogr.91, 5 (1974).

    Google Scholar 

  2. M. J. E. Golay, Report of November 15, 1956. Quoted inL. S. Ettre, Open Tubular Columns in Gas Chromatography, Plenum Press, New York, 1965; p. 3.

    Google Scholar 

  3. M. J. E. Golay, inV. J. Coates, H. J. Noebels, I. S. Fagerson (Editors), Gas Chromatography (1957 Lansing Symposium), Academic Press, New York, 1958; pp. 1–13.

    Google Scholar 

  4. L. S. Ettre, inW. G. Jennings (Editor), Applications of Glass Capillary Gas Chromatography, M. Dekker Inc., New York NY, 1981; pp. 1–47.

    Google Scholar 

  5. D. H. Desty, inH. P. Angelé (Editor), Gas Chromatographie 1958 (Leipzig Symposium), Akademie Verlag, 1959; pp. 176–184.

  6. A. Zlatkis, J. E. Lovelock, Anal. Chem.31, 620 (1959).

    Google Scholar 

  7. S. R. Lipsky, R. A. Landowne, J. E. Lovelock, Anal. Chem.31, 852 (1959).

    Google Scholar 

  8. R. D. Condon, Anal. Chem.31, 1717 (1959).

    Google Scholar 

  9. R. P. W. Scott, Nature (London)183, 1753 (1959).

    Google Scholar 

  10. R. P. W. Scott, G. S. F. Hazeldean, inR. P. W. Scott (Editor), Gas Chromatography 1960 (Edinburgh Symposium), Butterworths, London, 1960; pp. 144–161.

    Google Scholar 

  11. W. Averill, Instrument News12 (1), 6 (1960).

    Google Scholar 

  12. L. S. Ettre, W. Averill, inN. D. Cheronis (Editor), Proceedings of the 1961 Symposium on Microchemical Techniques, Interscience, New York NY, 1962; pp. 715–732.

    Google Scholar 

  13. W. Averill, inN. Brenner, J. E. Callen, M. D. Weiss (Editors), Gas Chromatography (1961 Lansing Symposium), Academic Press, New York NY, 1962; pp. 1–6.

    Google Scholar 

  14. L. S. Ettre, Instrument News13 (1a), 1 (1961).

    Google Scholar 

  15. L. S. Ettre, W. Averill, F. J. Kabot, Gas Chromatographic Analysis of Fatty Acids. GC Applications, No. GC-AP-001, The Perkin-Elmer Corp., Norwalk CT, 1962.

    Google Scholar 

  16. W. Averill, J. Gas Chromatogr.1 (1), 22 (1963).

    Google Scholar 

  17. D. Jentzsch, W. Hövermann, inM. van Swaay (Editor), Gas Chromatography 1962 (Hamburg Symposium), Butterworths, London, 1962; pp. 204–215.

    Google Scholar 

  18. D. Jentzsch, W. Hövermann, Die Anwendung von Makro-Golay-Säulen in der Gaschromatographie. Aus der Praxis —Für die Praxis, No. 19GC, Bodenseewerk Perkin-Elmer & Co., Überlingen, 1962.

    Google Scholar 

  19. D. Jentzsch, W. Hövermann, J. Chromatogr.11, 440 (1963).

    Google Scholar 

  20. R. D. Schwartz, D. J. Brasseaux, G. R. Shoemake, J. Gas Chromatogr.1 (1), 32 (1963);1 (2), 17 (1963).

    Google Scholar 

  21. A. Zlatkis, J. Q. Walker, J. Gas Chromatogr.1 (5), 9 (1963).

    Google Scholar 

  22. R. Teranishi, T. R. Mon, Anal. Chem.36, 1491 (1964).

    Google Scholar 

  23. J. C. Sternberg, R. E. Poulson, Anal. Chem.36, 1492 (1964).

    Google Scholar 

  24. A. Zlatkis, H. R. Kaufman, Nature (London)184, 2010 (1959).

    Google Scholar 

  25. E. Kováts, Meeting of the (British) Chromatography Discussion Group, Birmingham, April 21, 1961; seeH. Strickler, E. Kováts, J. Chromatogr.8, 289 (1962).

    Google Scholar 

  26. L. S. Ettre, E. W. Cieplinski, W. Averill, J. Gas Chromatogr.1 (2), 7 (1963).

    Google Scholar 

  27. E. R. Quiram, Anal. Chem.35, 593 (1963).

    Google Scholar 

  28. D. H. Desty, A. Goldup, B. H. F. Whyman, J. Inst. Petrol.45, 287 (1959).

    Google Scholar 

  29. D. H. Desty, A. Goldup, inR. P. W. Scott (Editor), Gas Chromatography 1960 (Edinburgh Symposium), Butterworths, London, 1960; pp. 162–183.

    Google Scholar 

  30. D. H. Desty, A. Goldup;W. T. Swanton, inN. Brenner, J. E. Callen, M. D. Weiss (Editors), Gas Chromatography (1961 Lansing Symposium), Academic Press, New York NY, 1962; pp. 105–135.

    Google Scholar 

  31. W. Averill, E. W. March, Chromatogr. Newslett.4, 20 (1976).

    Google Scholar 

  32. N. G. Johansen, Chromatogr. Newslett.7, 18 (1979).

    Google Scholar 

  33. N. G. Johansen, L. S. Ettre, R. Miller, J. Chromatogr.256, 393 (1983).

    Google Scholar 

  34. J. J. Franken, G. A. T. M. Rutten, inS. G. Perry, E. R. Adla (Editors), Gas Chromatography 1972 (Montreux Symposium), Applied Science Publishers, Barking, 1973; pp. 75–88.

    Google Scholar 

  35. K. Grob Jr., K. Grob, Chromatographia10, 250 (1977).

    Google Scholar 

  36. R. F. Adams, F. L. Vandemark, G. J. Schmidt, J. Chromatogr. Sci.15, 63 (1977).

    Google Scholar 

  37. C. P. M. Schutjes, E. A. Vermeer, J. A. Rijks, C. A. Cramers, inR. E. Kaiser (Editor), Capillary Chromatography (1981 Hindelang Symposium), Institute of Chromatography, Bar Dürkheim, 1981; pp. 687–702.

    Google Scholar 

  38. C. P. M. Schutjes, E. A. Vermeer, J. A. Rijks, C. A. Cramers, J. Chromatogr.253, 1 (1982).

    Google Scholar 

  39. C. A. Cramers, E. A. Vermeer, J. A. Rijks, G. J. Scherpenzer, C. P. M. Schutjes, Second Internat. Symposium on Capillar Chromatography, Terrytown NY, October 10–12, 1983.

  40. L. S. Ettre, Chromatographia17, 553 (1983).

    Google Scholar 

  41. L. S. Ettre, G. L. McClure, J. D. Walters, Chromatographia17, 560 (1983).

    Google Scholar 

  42. P. Sandra, I. Temmerman, W. Verstappe, J. High Resolut. Chromatogr./Chromatogr. Commun.6, 501 (1983).

    Google Scholar 

  43. G. L. McClure, N. H. Williams, W. M. Whitten, 35th Pittsburgh Conf. on Analytical Chemistry and Applied Spectroscopy, Atlantic City NJ, March 5–9, 1984; Abstracts, Paper No. 267.

  44. M. L. Duffy, E. Monke Jr., 35th Pittsburgh Conf. on Analytical Chemistry and Applied Spectroscopy, Atlantic City NY March 5–9, 1984; Abstracts, Paper No. 496.

  45. R. T. Palo, J. D. Walters, E. W. March, L. S. Ettre, J. High Resolut. Chromatogr./Chromatogr. Commun., in press.

  46. L. S. Ettre, J. E. Purcell, inJ. C. Giddings, R. A. Kelle (Editors), Advances in Chromatography, Vol. 10, M. Dekker Inc., New York NY, 1974; pp. 1–97.

    Google Scholar 

  47. GC Supplies Catalog No. 33, Ohio Valley Specialty Chemical Inc., Marietta, Ohio, 1984.

  48. L. S. Ettre, Open Tubular Columns in Gas Chromatographia, Plenum Press, New York NY, 1965; a p. 15.

    Google Scholar 

  49. L. S. Ettre, inA. B. Littlewood (Editor), Gas Chromatography 1966 (Rome Symposium), Inst. of Petroleum, London, 1967; pp. 115–118.

    Google Scholar 

  50. J. J. Van Deemter, F. J. Zuiderweg, A. Klinkenberg, Chem. Eng. Sci.5, 271 (1956).

    Google Scholar 

  51. A. I. M. Keulemans, Gas Chromatography, 2nd ed., Reinhold, New York NY, 1959; p. 194.

    Google Scholar 

  52. A. Klinkenberg, inR. P. W. Scott (Editor), Gas Chromatography 1960 (Edinburgh Symposium), Butterworths, London, 1980; pp. 182–183.

    Google Scholar 

  53. C. Horváth, Trennsäulen mit dünnen porösen Schichten for die Gaschromatographie. Inaugural Dissertation, J. W. Goefr. University, Frankfurt/Main, 1963.

    Google Scholar 

  54. I. Halász, C. Horváth, Anal. Chem.35, 499 (1963).

    Google Scholar 

  55. I. Halász, C. Horváth, German. Pat. 1,183,716 (1965); US Pat. 3,295,296 (1967).

  56. L. S. Ettre, J. E. Purcell, S. D. Norem, J. Gas Chromatogr.3, 181 (1965).

    Google Scholar 

  57. J. E. Purcell, L. S. Ettre, J. Gas Chromatogr.4, 23 (1966).

    Google Scholar 

  58. L. S. Ettre, J. E. Purcell, K. Billeb, J. Chromatogr.24, 335 (1966).

    Google Scholar 

  59. L. S. Ettre, J. E. Purcell, K. Billeb, Separation Sci.1, 77 (1966).

    Google Scholar 

  60. R. R. Freeman, Second Internat. Symposium on Capillary Chromatography, Terrytown NY, October 10–12, 1983.

  61. B. L. Ryder, J. Phillips, L. L. Plotczyk, M. Redstone, 35th Pittsburgh Conf. on Anal. Chemistry and Applied Spectroscopy, Atlantic City NJ, March 5–9, 1984; Abstract, Paper No. 497.

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  1. Chromatography Division, The Perkin-Elmer Corporation, 08656, Norwalk, CT, U.S.A.

    L. S. Ettre

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Ettre, L.S. Performance of open tubular columns as a function of tube diameter and liquid phase film thickness. Chromatographia 18, 477–488 (1984). https://doi.org/10.1007/BF02267232

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