Broad spectrum resolution of optical isomers using chiral high-performance liquid chromatographic bonded phases

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Abstract

Using a chiral recognition rationale, a chiral fluoroalcoholic bonded stationary phase has been devised which proves capable of separating the enantiomers of a large number of solutes including sulfoxides, lactones, and derivatives of alcohols, amines, amino acids, hydroxy acids, and mercaptans.

Chiral recognition being a reciprocal event, chiral stationary phases modeled after solutes resolvable upon the fluoroalcoholic columns successfully separate the enantiomers of a number of fluoroalcohols.

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    Presented at the 4th International Symposium on Column Liquid Chromatography, Boston, May 7-10, 979. The majority of the papers presented at this symposium has been published in J. Chromatogr., Vol. 185 (1979).

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