HRRI: A high-resolution β imager for biological applications

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Abstract

We have developed a high-resolution β position detector which combines a thin scintillator sheet and an intensified CCD. This device has been designed for molecular biology purposes (“in situ” hybridization). Therefore, the absolute detection efficiency, S/N ratio and spatial resolution have been studied in particular. With the first version of our detector, we achieved an intrinsic resolution of 10 μm with a relative efficiency for 35S of 99% (i.e. 18% absolute efficiency). We now present results in which another scintillator and a new triggering system have been adopted. The main result is that the absolute efficiency has been improved (up to ≈ 60% for 35S) and the background influence has been significantly reduced. These improvements can be observed on the biological image displayed in this paper.

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