Biochemical and Biophysical Research Communications
Assignment of the quaternary structure of hybrid hemoglobins: Implications for allosteric theories
References (29)
- et al.
J. Mol. Biol
(1973) - et al.
Biochem. Piophys. Res. Comm
(1971) - et al.
J. Biol. Chem
(1972) - et al.
Biochem. Biophys. Res. Comm
(1980) - et al.
J. Biol. Chem
(1969) Biochim. Biophys. Acta
(1959)- et al.
J. Inorg. Nucl. Chem
(1970) - et al.
Biochem. Biophys. Res. Comm
(1977) - et al.
J. Biol. Chem
(1975) J. Mol. Biol
(1971)
J. Biol. Chem
J. Mol. Biol
J. Mol. Biol
Biochem. Biophys. Res. Comm
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Liganded hemoglobin structural perturbations by the allosteric effector L35
2005, Biophysical JournalCitation Excerpt :Similar domain-dependent R- and T-like structural features have been previously reported. UV CD spectra of metal hybrid Hb, such as αFe→ZnβCO, αCO βFe→Zn, and αFe→ZnβFe→Zn, show a significant negative ellipticity band centered at 280 nm, analogous to T-state Hb (Fiechtner et al., 1980; Simolo et al., 1986), whereas other regions, such as Val (E11) and Asp (β89)-Tyr (α42), probed by NMR resonance and exchangeable proton, resemble the oxy R structure (Simolo et al., 1986). Additionally, studying the allosteric effector-induced changes of oxyHbA at the near-UV and Soret region CD spectra changes, Coletta et al. (1999) showed that the α1β2 interface of oxyHbA in the simultaneous presence of IHP and BZF mostly maintains a quaternary R-tetrameric structure, whereas the heme conformation conforms to that typical of the low-affinity structure at neutral pH. They demonstrated that IHP and BZF together induce a stabilization of a tertiary T-like conformation within a quaternary R-like structure (Coletta et al., 1999).
Stationary and time-resolved circular dichroism of hemoglobins
1994, Methods in EnzymologyKinetic-dynamic model for conformational control of an electron transfer photocycle: Mixed-metal hemoglobin hybrids
2008, Journal of Physical Chemistry BConformational dependence of hemoglobin reactivity under high viscosity conditions: The role of solvent slaved dynamics
2007, Journal of the American Chemical SocietyMetal ion reconstituted hybrid hemoglobins
1998, Progress in Inorganic ChemistryMetal ion environment in reconstituted hemoglobins and myoglobins
1990, Proceedings of the Indian Academy of Sciences - Chemical Sciences