A correlation between the sedimentation coefficient of deoxyribonucleic acid and its paper chromatographic migration

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Abstract

A method for the paper chromatographic examination of DNA is described. The rate of migration of DNA on paper has been found to be related to the sedimentation coefficient. Accordingly, a rough estimate of the sedimentation coefficient of DNA may be obtained without recourse to ultracentrifugation.

References (39)

  • E. Chargaff et al.

    J. Biol. Chem

    (1950)
  • K. Felix et al.

    Progr. in Biophys. and Biophys. Chem

    (1956)
  • S.M. Beiser et al.

    Biochim. et Biophys. Acta

    (1959)
  • N.B. Kurnick

    Arch. Biochem. Biophys

    (1953)
  • E. Chargaff et al.

    J. Biol. Chem

    (1951)
  • V.N. Schumaker et al.

    Biochim. et Biophys. Acta

    (1957)
  • S.A. Rice et al.

    J. Am. Chem. Soc

    (1957)
    P. Doty et al.
  • P. Doty et al.
  • A. Bendich et al.
  • A. Bendich et al.

    J. Am. Chem. Soc

    (1958)
  • T. Wieland
  • K.C. Smith et al.

    J. Am. Chem. Soc

    (1953)
  • M. Privat de Garilhe et al.

    J. Biol. Chem

    (1955)
  • H.S. Rosenkranz et al.

    J. Am. Chem. Soc

    (1959)
  • E.R.M. Kay et al.

    J. Am. Chem. Soc

    (1952)
  • H. Schwander et al.

    Helv. Chim. Acta

    (1950)
  • G.R. Wyatt et al.

    Biochem. J

    (1953)
  • R. Laskov et al.

    Biochim. et Biophys. Acta

    (1954)
  • M. Grunberg-Manago et al.

    Biochim. et Biophys. Acta

    (1956)
  • Cited by (2)

    This investigation was supported by funds from the American Cancer Society, National Cancer Institute, National Institutes of Health, Public Health Service (Grant No. CY-3190), and from the Atomic Energy Commission (Contract No. AT, (30-1), 910).

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