Dexamethasone directly inhibits snake venom phospholipase A
References (17)
- et al.
J. Biol. Chem
(1977) - et al.
Biochem. Biophys. Res. Commun
(1982) - et al.
Biochem. Biophys. Res. Commun
(1983) Life Sci
(1982)- et al.
Biochem. Pharmacol
(1980) - et al.
J. Clin. Invest
(1963) - et al.
- et al.
There are more references available in the full text version of this article.
Cited by (10)
Inflammatory mediators in the pronociceptive effects induced by Bothrops leucurus snake venom: The role of biogenic amines, nitric oxide, and eicosanoids
2021, ToxicologyCitation Excerpt :In agreement with our findings, previous studies have shown that the treatment with dexamethasone reduces the hyperalgesia induced by the venoms of B. jararaca (Teixeira et al., 1994) and B. asper (Chacur et al., 2001), as well as by an isolated toxin from B. pirajai venom (Bernardes et al., 2015). Dexamethasone has been shown to directly inhibit the enzymatic activity of snake venom PLA2 toxins (Kato et al., 1985). Nevertheless, Zhang et al. (2018) have demonstrated that the antiedematogenic effect of a selective snake venom PLA2 inhibitor was greater than that of dexamethasone in a carrageenan-induced model of inflammation, suggesting that dexamethasone does not fully inhibit secreted PLA2.
Dantrolene and mepacrine antagonize the hemolysis of human red blood cells by halothane and bee venom phospholipase A<inf>2</inf>
1987, Toxicology and Applied PharmacologyGlucocorticoid-induced modulation of the beta-adrenergic adenylate cyclase response of epidermis: Its relation to epidermal phospholipase A<inf>2</inf> activity
1986, Journal of Investigative DermatologyChapter 8. Pulmonary and Antiallergy Agents
1986, Annual Reports in Medicinal ChemistryProtective effect of a new hypothalamic peptide against cobra venom and trauma-induced neuronal injury
2001, Neurochemical Research
Copyright © 1985 Published by Elsevier Inc.