Biochemical and Biophysical Research Communications
Volume 116, Issue 2, 31 October 1983, Pages 500-506
Decaprenyl pyrophosphate synthetase from mitochondria of pig liver
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Isotopic labelings for mechanistic studies
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2021, Trends in CancerCitation Excerpt :There are also studies of the addition of isopentenyl pyrophosphate to tRNA, a process known as isopentenylation, and its role in cancer [28]. While these studies may result in niche applications of statins, they do not explain the more widely reported dependency on GGPP, as ubiquinone and dolichol can be derived from FPP [60–63] (Figure 1). GGPP is utilized for the conversion of vitamin K1 to vitamin K2 [64] by UBIAD1, an enzyme that also directs HMGCR degradation [65,66].
Isoprenyl diphosphate synthases
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Copyright © 1983 Published by Elsevier Inc.