Elsevier

Experimental Cell Research

Volume 142, Issue 2, December 1982, Pages 464-468
Experimental Cell Research

Preliminary note
Thermal tolerance and specific protein synthesis in Chinese hamster fibroblasts exposed to prolonged hypoxia

https://doi.org/10.1016/0014-4827(82)90390-1Get rights and content

Abstract

We have demonstrated that prolonged hypoxia can induce both thermotolerance and the synthesis of heat shock proteins in HA-1 Chinese hamster ovary cells. This tolerance was transient in nature: upon reaeration at 37 °C, HA-1 cells regained their “normal” heat response within 34 h.

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This work was supported by funds from the University of California Academic Senate and School of Medicine, by grants from the USPHS (CA 20529, CA 17227 and CA 31397).

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