Two insecticidal monoterpenes, telfairine and aplysiaterpenoid A, from the red alga Plocamium telfairiae: Structure elucidation, biological activity, and molecular topographical consideration by a semiempirical molecular orbital study☆
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Insecticidal effects of natural products in free and encapsulated forms: an overview
2022, Journal of Natural Pesticide ResearchToxic assessment, growth disrupting and neurotoxic effects of red seaweeds’ botanicals against the dengue vector mosquito Aedes aegypti L.
2020, Ecotoxicology and Environmental SafetyCitation Excerpt :Aplysia terpenoid and telfairine, obtained from Plocamium telfairiae (red seaweed) showed similar cyclodiene (an organochlorine insecticide) like mode of action blocking GABA-gated channel with strong larvicidal activity against Ae. gambiae (Watanabe et al., 1990). As a result, a hyperexcitation of central nervous system and convulsion is observed leading to death (Bloomquist, 1993).
Bioactive compounds in seaweeds: An overview of their biological properties and safety
2020, Food and Chemical ToxicologyCitation Excerpt :It is also important to point out that many bioactive compounds, especially the terpenoids, have not been tested in toxicological studies. Considering the fact that some of these compounds are known to possess insecticidal properties such as mertensene, violacene (Argandona et al., 2000), telfairine (Watanabe et al., 1989), aplysiaterpenoid A (Watanabe et al., 1990), elatol (Bianco et al., 2013), it is necessary that future studies aim to determine their safety profile in vitro and on animal species. Marine macroalgae or seaweeds are considered as one among the economically important biological resources which offer an extensive assortment of phytonutrients and phytochemicals comprising of vitamins, proteins, micro and macro elements, poly- and oligosaccharides, polyunsaturated fatty acids, terpenoids, alkaloids, polyphenols especially phlorotannins and polyamines with potential pharmacological properties.
Larvicidal and oviposition deterrent activity of sesquiterpenes from the red seaweed Laurencia johnstonii against Aedes aegypti
2024, Journal of Applied Phycology
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A part of these results was presented at the 16th International Symposium on the Chemistry of Natural Products, IUPAC, Kyoto, Japan,1988.