Some immediate effects of a blood donation on plasma chemistry

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Abstract

  • 1.

    1. Plasma urea and electrolyte levels have been determined on blood samples collected immediately before and after the donation of 420 ml blood by 106 subjects.

  • 2.

    2. Significant differences were relatively infrequently found in the case of urea, CO2 capacity, chloride and sodium levels, but the potassium concentration was found to alter by more than 0.2 mequiv/l in 38% of the donors, and by at least 0.5 mequiv/l in 15% of the donors.

  • 3.

    3. Sometimes concentrations were increased following donation and sometimes they fell.

  • 4.

    4. It is suggested that muscular activity in the forearm muscles and/or secretion of adrenalin and noradrenalin by the adrenal medulla probably account for most of the findings.

  • 5.

    5. It is concluded that blood samples obtained at the end of a donation of blood should not be assumed to be suitable for the establishment of normal values.

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