ArticleDual effects of (D-Ala2,Met5)-enkephalinamide on CRF and ACTH secretion
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Intracerebroventricular met-enkephalin administration modulates adjuvant arthritis
2000, Brain ResearchCitation Excerpt :The median eminence is rich in opioid receptors [1]. Many studies showed that met-enk has major effects on the release of many pituitary hormones including adrenocorticotropic hormone (ACTH) [9,11], growth hormone [8], prolactin [8], thyrotropin [23] and luteinizing hormone [8]. In the hypothalamus enkephalin immunoreactivity has been localized in the parvocellular neurons of the hypothalamic paraventricular nucleus which projects on to the median eminence [13], the site where hypothalamic releasing factors are secreted into the portal blood, hence the anterior pituitary gland.
Developmental regulation of preproenkephalin mRNA in the ovine paraventricular nucleus: effects of stress and glucocorticoids
1995, Developmental Brain ResearchRegulation of the hypothalamic corticotropin-releasing hormone neurosecretory system
1993, Progress in NeurobiologyThe central effect of methionine-enkephalin on NK cell activity
1992, Brain Research
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