Effect of growth rate on the acid-soluble nucleotide composition of Salmonella typhimurium

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Abstract

The acid-soluble nucleotide composition of Salmonella typhimurium was determined for six different media which supported growth at generation times varying from 30 to 240 min. On a molar basis (μmoles per g dry wt.) the concentrations of UTP, GTP, and UDPG increased with an increase in the growth rate. ATP was constant for all media except broth where it doubled. ADP was constant at all growth rates.

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This investigation was carried out during the tenure of a Postdoctoral Fellowship from the National Institute of Allergy and Infectious Diseases, United States Public Health Service.

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Present address: Department of Animal Science, Auburn University, Auburn, Ala., U.S.A.

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