Purification et études des mucines de kystes bronchogéniquesPurification and study of bronchogenic cysts mucins

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Abstract

Glycoproteins rich in fucose, or N-acetylneuraminic acid or sulfate groups were isolated form three bronchogenic cysts. The polypeptide backbone of these molecules was rich in hydroxyaminoacids (25–40%) and devoid of cystein. Arginine was the only n-terminal group detectable. The carbohydrate-peptide linkages of the different species of glycoproteins were studied and were alkali-labile. Sulfate-rich glycoproteins had a lower ratio Thr/Ser, fewer carbohydrate-peptide linkages, longer carbohydrate chains and higher amounts of arginine. The linkages seem to involve mainly serine. The ratios Thr/Ser and Pro/Gly were similar.

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