Age-related changes in the regulation of cholesterol metabolism in rats
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Cited by (37)
Meat quality and Raman spectroscopic characterization of Korat hybrid chicken obtained from various rearing periods
2021, Poultry ScienceCitation Excerpt :In contrast, changes in the cholesterol content in thigh meat were subtle (P > 0.05; Figure 1). The reduction of cholesterol with advancing age has been reported by Choi et al. (1987) who found an impairment in enzymes relevant for cholesterol synthesis in adult rats, including acetoacetyl-CoA synthetase, acetoacetyl-CoA thiolase, 3-hydroxyl-3-methylglutryl-coenzyme A (HMG-CoA) reductase, HMG-CoA synthase, mevalonate kinase, and cholesterol 7α-hydroxylase. Moreover, thigh meat showed higher cholesterol content than breast meat in both breeds.
Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases
2018, International Review of Cell and Molecular BiologyCitation Excerpt :Moreover, a number of liver enzymes are involved and affected by aging (Schmucker, 2001). Choi et al. (1987) have found a significant decrease in the enzymatic activity of cholesterol 7α-hydroxylase in rats 5–32 weeks of age. In the study by Wang (2002), gallstone-susceptible C57L mice and resistant AKR mice of both genders split into young adult, older adult, and aged groups (8, 36, and 50 weeks of age, respectively) were each fed a lithogenic diet for 8 weeks.
Age-related alteration in hepatic acyl-CoA: Cholesterol acyltransferase and its relation to LDL receptor and MAPK
2005, Mechanisms of Ageing and DevelopmentAging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice
2002, Journal of Lipid ResearchAge-related changes in mRNA, protein and catalytic activity of hepatic neutral cholesterol ester hydrolase in male rats: Evidence for transcriptional regulation
1996, Biochimica et Biophysica Acta - Lipids and Lipid MetabolismAge-related changes in blood and liver lipids of male wistar rats
1993, Archives of Gerontology and Geriatrics