Elsevier

Current Opinion in Cell Biology

Volume 5, Issue 6, December 1993, Pages 1023-1028
Current Opinion in Cell Biology

Transdifferentiation

https://doi.org/10.1016/0955-0674(93)90087-7Get rights and content

Abstract

Recent progress in studies of development and differentiation has greatly stimulated analysis of transdifferentiation, and more cell types capable of transdifferentiation have been documented. Growth factors must be essential, key factors in the regulation of the transdifferentiation process, in cooperation with components of the extracellular matrix, which helps to stabilize the differentiated state of tissues. Trials to induce transdifferentiation artificially by transfection of genes have also begun.

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