Constitution of Solasonine (Solanine-s)

Abstract

FURTHER analyses of the gluco-alkaloid, solasonine (solanine-s), the aglycone, solasodine (solanidine-s) and its derivatives are in agreement more with the molecular formula;, C₄₅H₇₃O₁₆N, for the glycone and C₂₇H₄₃O₂N for the aglycone. Formulæ, C₂₇H₄₅O₂N and C₂₆H₄₃O₂N, for the aglycone and corresponding formulæ for the gluco-alkaloid are not yet excluded but are less likely on theoretical grounds. From biochemical considerations a formula containing 27 carbon atoms is also to be preferred since there are no well-authenticated steroid derivatives, with the exception of solanocapsine and solanocapsidine¹ to which the same argument may apply, containing 26 carbon atoms. Since solasonine gives rise to glucose, galactose, rhamnose and solasodine on hydrolysis², it must now be built up from these sugars and one molecule of the aglycone and not two as suggested by Oddo.