Abstract
A NUMBER of papers1 from this laboratory have reported the preparation from yeast and malt-combings of fractions which stimulate the respiration of yeast and of animal tissues, particularly of skin. A study of these fractions appears to indicate the existence of a multiplicity of respiratory factors. The fractions studied thus far have been water-soluble and thermostable. They have all contained nitrogen and phosphorus, but the fractions have been manifestly impure and it has been difficult to correlate the respiratory activity with chemical properties except to indicate that protein probably plays no part. On the other hand, it has been possible to correlate the proliferation-promoting activity of preparations from yeast with nucleic acid-like materials containing guanine, adenine, phosphorus and pen-toses, and having a maximum in ultra-violet absorption2 at 2600 A.
Similar content being viewed by others
Article PDF
References
Fardon, Norris, Loofbourow and Ruddy, NATURE, 139, 589 (1937). Norris and Kreke, Studies Inst. Divi ThomÅ", 1, 137 (1937). Cook, Hart and Joly, Proc. Soc. Exptl. Biol. Med., 38, 169 (1938). Cook, Kreke, and Nutini, Studies Inst. Divi Thomce, in the Press. Cook and Kreke, ibid., in the Press.
Cook, Loofbourow, and Stimson, 10th International Congress of Chemistry, Rome, May, 1938. Loofbourow, Cook, and Stimson, in the Press.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
COOK, E., KREKE, C. Fatty Acids from Yeast as Respiratory Factors. Nature 142, 719 (1938). https://doi.org/10.1038/142719a0
Issue Date:
DOI: https://doi.org/10.1038/142719a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.