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Phosphatides in Myelin Sheaths and Repartition of Sphingomyelin in the Brain

Nature volume 198, pages 586–587 (1963)Cite this article

Abstract

OUR work on the phospholipids of the brain of the adult rat during post-natal development led us to examine their distribution in the various sub-cellular fractions. Tyrrell and Richter1, as well as Debuch and Stammler2, have noted the distribution of phospholipids in the brain nuclei; Biran and Bartley3, August, Davison and Williams4 their distribution in mitochondria and micro-somes; Harth, Borkowski, Mardell and Mandel5 their distribution in nuclei, mitochondria, microsomes and myelin sheaths; finally, Patterson and Fineau6 their distribution in the various sub-cellular fractions of the optic nerve. In the work recorded here, we present results obtained from the examination of the distribution of sphingomyelin in the various sub-cellular fractions of rat brain.

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References

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Authors and Affiliations

  1. Faculté de Médecine, Institut de Chimie Biologique, Strasbourg

    J. L. NUSSBAUM, R. BIETH & P. MANDEL

Authors
  1. J. L. NUSSBAUM
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  2. R. BIETH
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  3. P. MANDEL
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NUSSBAUM, J., BIETH, R. & MANDEL, P. Phosphatides in Myelin Sheaths and Repartition of Sphingomyelin in the Brain. Nature 198, 586–587 (1963). https://doi.org/10.1038/198586a0

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