Abstract
QUANTITATIVE estimation of haptoglobins, a group of serum alpha-2 mucoproteins capable of binding hæmoglobin, is at present based either directly or indirectly on the peroxidase activity of the hæmoglobin–haptoglobin complex1–3. Recent investigations in this laboratory into the characteristics and formation of this complex emphasized the need for a more direct analytical method. The most appropriate characteristic of haptoglobin, its ability to bind hæmoglobin, was selected as the basis for an analytical procedure using hæmoglobin labelled with radioactive iron-59.
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SASS, M., SPEAR, P. Estimation of Haptoglobin using Hæmoglobin labelled with Radioactive Iron-59. Nature 193, 285–286 (1962). https://doi.org/10.1038/193285a0
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DOI: https://doi.org/10.1038/193285a0
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