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Determination of Molecular Weights of Polysaccharides by Over-oxidation with Periodate

Abstract

IN addition to its capacity to oxidize α-glycol groups, periodate oxidizes C—H groups flanked by two α-carbonyl groups1. Such structures are exposed in the reducing-end units of 1 : 2-, 1 : 3- or 1 : 4-linked aldohexopyranose oligosaccharides when the α-glycol groups have been oxidized.

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PARRISH, F., WHELAN, W. Determination of Molecular Weights of Polysaccharides by Over-oxidation with Periodate. Nature 183, 991–992 (1959). https://doi.org/10.1038/183991a0

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