Abstract
THE electrical activity of frog spinal ganglion cells is maintained, and even enhanced, when the external sodium has been totally replaced by equimolar amounts of either choline or tetraethylammonium1. Further investigations suggested that quaternary ammonium ions do not actually substitute for sodium as carriers of the action current, but probably exert a pharmacological action on the membrane or in the perikaryon2.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Koketsu, K., Cerf, J. A., and Nishi, S., Nature, 181, 703 (1958).
Koketsu, K., Cerf, J. A., and Nishi, S., J. Neurophysiol. (in the press).
Lorente de Nó, R., J. Cell Comp. Physiol., 33, Supp. (1949). Larramendi, L. M. H., Lorente de Nó, R., and Vidal, F., Nature, 178, 316 (1956). Lorente de Nó, R., Vidal, F., and Larramendi, L. M. H., ibid., 179, 737 (1957).
Fatt, P., and Katz, B., J. Physiol., 120, 171 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KOKETSU, K., CERF, J. & NISHI, S. Electrical Responses of Neuron Cell-Bodies in Sodium-free Media. Nature 181, 1798–1799 (1958). https://doi.org/10.1038/1811798b0
Issue Date:
DOI: https://doi.org/10.1038/1811798b0
This article is cited by
-
Synaptic Transmission in a Sodium-free Medium
Nature (1958)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.