Abstract
ALTHOUGH it is known that lysergic acid diethylamide enters the brain, the mechanism by which it acts to produce the psychotic patterns in man is unknown. Experiments which are designed to investigate the brain process in the intact animal might lead to a concept that could be developed to study the chemical process originating or connected with clinically occurring schizophrenia.
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References
Abramson, H. A., and Evans, L. T., Science, 120, 991 (1954). Evans, L. T., Geronimus, L. H., Kornetsky, C., and Abramson, H. A., ibid., 12, 28 (1956).
Abramson, H. A., Sklarofsky, B., Baron, M. O., and Gettner, H. H., Amer. Med. Assoc. Arch. Neurol. and Psychiat., 77, 445 (1947).
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ABRAMSON, H., WEISS, B. & BARON, M. Comparison of Effect of Lysergic Acid Diethylamide with Potassium Cyanide and other Respiratory Inhibitors on the Siamese Fighting Fish. Nature 181, 1136–1137 (1958). https://doi.org/10.1038/1811136b0
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DOI: https://doi.org/10.1038/1811136b0
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