Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Soluble Antigens in Microsomes and Other Cell-Fractions of Rat Liver

Nature volume 181, pages 491–492 (1958)Cite this article

Abstract

IT has been known for some time that particulate material sedimentable by high speed from tissue cells has characteristic immunological properties, and the antigenic specificity of isolated cell fractions has been studied in a variety of normal and tumour tissues1. These investigations not unexpectedly revealed a high degree of antigenic complexity of the different cell fractions, making further analysis difficult by the methods at hand. However, the results seemed encouraging enough to warrant an extension of the immunological work to the various soluble antigens characterizing different parts of the cell. An investigation of this sort has been carried out in our laboratory, and a detailed report of it will be published later.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Dulaney, A. D., Goldsmith, Y., Arnesen, K., and Buxton, A. L., Cancer Res., 9, 217 (1949). Malmgren, R. A., Bennison, B. E., Andersson, B. F., and Risley, C. C., J. Nat. Cancer Inst., 11, 1277 (1951). Weiler, E., Z. Naturforsch., 7b, 324 (1952). Nungester, W. J., and Fisher, H., Cancer Res., 14, 284 (1954).

    CAS  PubMed  Google Scholar 

  2. Palade, G. E., and Siekevitz, Ph., J. Biophys. Biochem. Cytol., 2, 171 (1956).

    Article  CAS  Google Scholar 

  3. Korngold, L., and Lipari, R., Cancer Res., 15, 159 (1955).

    CAS  PubMed  Google Scholar 

  4. Uriel, J., and Grabar, P., Ann. Inst. Pasteur, 90, 427 (1956).

    CAS  Google Scholar 

  5. Rondle, C. J. M., and Carman, B. J., Experientia, 12, 443 (1956).

    Article  Google Scholar 

  6. Ouchterlony, Ö., Acta Path. Microbiol. Scand., 32, 231 (1953). Wilson, M. W., and Pringle, B. H., J. Immunol., 77, 324 (1956). Korngold, L., ibid., 77, 119 (1956). Korngold, L., and Van Leeuwen, G., ibid., 78, 172 (1957).

    Article  CAS  Google Scholar 

  7. Siekevitz, Ph., and Watson, M., J. Biophys. Biochem. Cytol., 2, 639 (1956).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. V. D'AMELIO: Swedish Institute Fellow, 1956–57

Authors and Affiliations

  1. Wenner-Gren Institute for Experimental Biology, University of Stockholm,

    P. PERLMANN & V. D'AMELIO

  2. Istituto Anatomia Comparata, Palermo

    V. D'AMELIO

Authors
  1. P. PERLMANN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. D'AMELIO
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

PERLMANN, P., D'AMELIO, V. Soluble Antigens in Microsomes and Other Cell-Fractions of Rat Liver. Nature 181, 491–492 (1958). https://doi.org/10.1038/181491a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/181491a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing