Abstract
IT has been shown1 that, by the action of chymotrypsin, insulin is broken down into a number of peptide fragments of comparatively small molecular weight, and a more massive residue. The higher molecular weight material can be precipitated by means of trichloro-acetic acid. Attempts have been made to separate the lighter peptide mixture, and the most effective method so far found has been paper partition chromatography2.
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Butler, J. A. V., Dodds, E. C., Phillips, D. M. P., and Stephen, J. M. L., Biochem. J. (in the press).
Consden, R., Gordon, A. H., and Martin, A. J. P., Biochem. J., 38, 224 (1944).
De Ment, J., "Fluorescent Chemicals and their Applications" (New York, 1942).
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PHILLIPS, D. Use of Ultra-Violet Fluorescence in Paper Chromatography. Nature 161, 53 (1948). https://doi.org/10.1038/161053a0
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DOI: https://doi.org/10.1038/161053a0
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