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Biological Sciences: New Type of Compound with Strong Sweetness

Nature volume 233, pages 619–620 (1971)Cite this article

Abstract

CHEMISTS have long been interested in sweet substances to be used in place of sugar for medical and dietary purposes, and several such substances have been found in natural sources or as synthetic compounds. Sodium saccharin, sodium cyclohexylsulphamate, glycyrrhizin1 (V), stevioside2 (VI), naringin dihydrochalcone3 (VII), neohesperidine dihydrochalcone3 (VIII), and L-aspartyl-L-phenylalanine methyl ester4 (IX) are well known as sweeteners, some of which have been put to practical use. We wish to report a new type of sweet compound with a different structure.

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References

  1. Beck, K. M., in Encyclopedia of Chemical Technology, second ed., 19 (edit. by Mark, H. F., Mcketta, jun., J. J., and Othmer, D. F.), 602 (Wiley, New York, 1969).

    Google Scholar 

  2. Wood, jun., H. B., Allerton, R., Diehl, H. W., and Fletcher, jun., H. G., J. Org. Chem., 20, 875 (1955); Vis, E., and Fletcher, jun., H. G., J. Amer. Chem. Soc., 78, 4709 (1956).

    Article  CAS  Google Scholar 

  3. Horowitz, R. M., and Gentili, B., J. Agric. Food Chem., 17, 696 (1969).

    Article  CAS  Google Scholar 

  4. Mazur, R. H., Schlatter, J. M., and Goldkamp, A. H., J. Amer. Chem. Soc., 91, 2684 (1969).

    Article  CAS  Google Scholar 

  5. Tahara, A., and Ohtsuka, Y., Chem. Pharm. Bull. (Tokyo), 18, 859 (1970).

    Article  CAS  Google Scholar 

  6. Beck, K. M., in Encyclopedia of Chemical Technology, 19 (edit. by Mark, H. F., Mcketta, jun., J. J., and Othmer, D. F.), 594 (Wiley, New York, 1969).

    Google Scholar 

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Authors and Affiliations

  1. Rikagaku Kenkyusho, (The Institute of Physical and Chemical Research), Wako-shi, Saitama-ken

    AKIRA TAHARA, TADASHI NAKATA & YASUO OHTSUKA

Authors
  1. AKIRA TAHARA
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  2. TADASHI NAKATA
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  3. YASUO OHTSUKA
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TAHARA, A., NAKATA, T. & OHTSUKA, Y. Biological Sciences: New Type of Compound with Strong Sweetness. Nature 233, 619–620 (1971). https://doi.org/10.1038/233619a0

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