Abstract
A MAJOR episode of DNA synthesis occurs during the interphase preceding meiosis1–4. Additional periods of synthesis have been detected by autoradiography during leptotene, zygotene or pachytene in newt5, man6 and mouse7. In Lilium and Trillium separate periods of synthesis have been demonstrated at zygotene and pachytene by 32P-phosphate labelling followed by DNA extraction8. Others have failed to detect prophase synthesis autoradiographically3,4, presumably because of the low level of label incorporation during synthesis of amounts of DNA estimated to represent 0.3–2.0% of the total nuclear DNA content5,9.
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RILEY, R., BENNETT, M. Biological Sciences: Meiotic DNA Synthesis. Nature 230, 182–185 (1971). https://doi.org/10.1038/230182a0
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DOI: https://doi.org/10.1038/230182a0
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