Abstract
IT has been shown that ‘Triton- WR 1339’, a non-ionic surf ace-active agent, induces high hyperlipæmia in rabbits1, rats2, mice3, guinea pigs1,4 and dogs5. Typical atheromasic changes of the aorta, coronary and pulmonary arteries have been demonstrated in ‘Triton’-treated dogs5. These findings are of some interest, since dogs are usually less susceptible to atherosclerosis, and the atheromasic changes have been obtained in aimals fed with a normal diet.
Similar content being viewed by others
Article PDF
References
Kellner, A., Correll, J. W., and Ladd, A. T., J. Exp. Med., 93, 373 (1951).
Friedman, M., and Byers, S. O., J. Exp. Med., 97, 117 (1953).
Hirsch, R. L., and Kellner, A., J. Exp. Med., 104, 15 (1959).
Patnode, R. A., Hudgins, P. C., and Yanicki, B. W., J. Exp. Med., 107, 33 (1958).
Scanu, A., Oriente, P., Szajewski, J. M., McKormack, L. J., and Page, I. H., J. Exp. Med., 114, 279 (1961).
Cali', A., Riv. Anat. Pat. Oncol., 5, 6 (1952).
Cali', A., No. 17, Sez. Perug. Soc. Ital. Biol. Sper., Perugia, edit. by Simonelli (1955).
Seifter, J., Baeder, D. H., Beckfield, W. J., Sharma, S. P., and Enrich, W. E., Proc. Soc. Exp. Biol. Med., 83, 468 (1953).
Adlersberg, D., Wang, C. I., and Strauss, L., J. Mount Sinai Hasp., 24, 655 (1957).
Zemplenyi, T., J. Atheroscler. Res., 2, 2 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROSSI, G., ORIENTE, P., CUZZUPOLI, M. et al. Failure to induce Atherosclerosis in ‘Triton’ Hyperlipæmic Guinea Pigs. Nature 203, 416 (1964). https://doi.org/10.1038/203416a0
Issue Date:
DOI: https://doi.org/10.1038/203416a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.