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Digitale Medien

The C-terminal part of the CDC25 gene product has Ras-nucleotide exchange activity when present in a chimeric SDC25-CDC25 protein (1993)

Boy-Marcotte, Emmanuelle ; Buu, Antoinette ; Soustelle, Christine ; [weitere]

Springer

Current genetics 23 (1993), S. 397-401

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Details

ISSN: 1432-0983

Schlagwort(e): Homoeologous recombination ; Ras ; SDC25 ; CDC25

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract The CDC25 gene from S. cerevisiae encodes an activator of Ras proteins. The C-terminal part of a structurally-related protein encoded by the SDC25 gene is characterised by a Ras-guanine nucleotide exchange activity in vitro whereas the C-terminal part of CDC25 gives no detectable exchange activity. A chimera between the 3′ regions of these two genes was constructed by homeologous recombination. This chimeric gene suppresses cdc25 mutations. When expressed in E. coli, the chimeric product is detectable by antibodies directed against the carboxy-terminal CDC25 peptide and has an exchange-factor activity on the Ras2 protein. Therefore, the carboxy-terminal parts of both the CDC25 and the SDC25 gene products are structurally and functionally similar. The CDC25 part of the chimeric protein contains an intrinsic guanine exchange factor which does not require an additional cofactor.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00312625

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Digitale Medien

Onderzoekingen over stuifbrand (1944)

Oort, A. J. P.

Springer

European journal of plant pathology 50 (1944), S. 73-106

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Details

ISSN: 1573-8469

Schlagwort(e): Dwerg ; Gemiddelde ; Gewas ; „Gezond” ; Graad van aantasting ; Herkomst ; Herstel ; Kieming ; Kiemplant ; Klein ; Overgevoelig ; Physio ; Ras ; Rijping ; Stuifbrand ; Vatbaar ; Volwassen plant ; „Ziek” ; dwarf ; mean ; crop ; in relation to seedlings: normal ; degree of attack ; origin ; recovering ; germination ; seedling ; small ; hypersensitive ; physiologic race ; variety ; maturation ; smut ; susceptible ; mature plant ; in relation to seedlings: abnormal