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  • Articles: DFG German National Licenses  (7)
  • Breast tumors
  • Cutaneous wrinkles
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Aesthetic plastic surgery 20 (2004), S. 377-384 
    ISSN: 1432-5241
    Keywords: Mastoplasty ; Vertical scar ; Cutaneous folds ; Cutaneous wrinkles ; Puckering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper presents a series of 54 consecutive cases of vertical mastoplasty carried out over the period February 1994 to April 1995. In 30 cases breast reduction was performed, in 19 pure mastopexy, and in the remaining 5, a mastopexy-breast augmentation with a silicon gel prosthesis was carried out. The parameters used for analyzing the persistence of vertical scarring were: inframammary cutaneous folds, wrinkling of the skin, and puckering at 1, 3, and 6 months during the postoperative period. An attempt has been made to establish how the vertical scar has evolved over this period. The study done by age groups as well as the study of the breast's cutaneoglandular characteristics provides data as to with which morphotype and worst results were obtained.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Aesthetic plastic surgery 20 (2004), S. 391-397 
    ISSN: 1432-5241
    Keywords: Breast reduction ; Breast tumors ; Breast tumor screening ; Mammography ; Ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We conducted a retrospective study to evaluate the diagnosability of breast tumors after breast reductions as this is a frequent surgical procedure. The data should shed light on the hypothesis that routine screening methods concerning the diagnosis of breast tumors prove more difficult after breast operations. All women who had undergone breast reduction at our department between January 1989 and December 1994 were examined. During this period we counted 166 patients; the majority of them (n = 144) had undergone a bilateral breast reduction and the rest of them (n = 22) a unilateral breast reduction for various reasons. After the operation, all patients were checked in standardized intervals. Those who developed any kind of breast mass (n = 6) were recorded and examined by ultrasound and mammography, and occasionally by an additional fine-needle biopsy. In case any doubt about the dignity had remained, an excisional biopsy was carried out. In none of our patients was it possible to get a precise diagnosis of an ill-defined mass with ultrasound. With mammography, some of the existing masses, which were really scars, mimicked different kinds of tumors, and once a carcinoma was initially interpreted as scar tissue with oil cysts. The diagnosis of breast masses after breast reductions with routinely used screening methods has proved to be more difficult as breast reductions lead to architectural alterations of the remaining breast parenchyma. Such alterations can and should be documented shortly after the operation so that later occurring tumors are distinguished more easily. Therefore, a basic mammography 3 months after each breast reduction has to be claimed in order to facilitate further breast tumor diagnosis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 126 (2000), S. 291-297 
    ISSN: 1432-1335
    Keywords: Key words Estrogen receptor ; Exon truncations ; Breast tumors ; African American women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Several recent reports have shown that the mortality rate with breast cancer is about three times higher in African American women than in other populations. In addition, the available data also indicate that the tumors are very aggressive and poorly differentiated with a very low frequency of hormone receptors. To gain an insight into the factors that may be responsible for their aggressive tumors, we investigated the transcript profiles of the estrogen receptor (ER), the most important prognostic factor in breast cancer, in the tumors derived from African American women. We analyzed 24 immunohistochemically ER+ and 6 ER− malignant tumors for ER mRNA by reverse transcription polymerase chain reaction using a number of primer pairs. For comparative purposes, 20 ER+ malignant tumor issues derived from Caucasian patients were also included. Our results showed that only 15 of the ER+ tumors from African American women patients had full-length wild-type receptor transcripts and the others exhibited alterations/truncations in exon 8. We also found that the majority of tumors that had alterations/truncations in exon 8 did not express the naturally occurring, more abundant exon 7 deletion transcript. Most of the tumors expressed exon 2, exons 2–3, and exon 5 deletion variant transcripts. Unexpectedly, 2 of the 6 immunohistochemically ER− tumors showed full-length wild-type receptor mRNA but none of the variant transcripts.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 11 (1996), S. 109-111 
    ISSN: 1437-9813
    Keywords: Cystosarcoma phylloides ; Fibroadenoma ; Breast tumors ; Adolescents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The management of adolescent females with giant cystosarcoma phylloides remains controversial. Since in this age group the overwhelming majority of these neoplasms are benign, aesthetic outcome is as important as adequate tumor resection. Traditional, treatment has been wide local excision, which may lead to substantial breast deformity. In addition, inadequate planning with improper incision placement may result in visible scarring and impair immediate or subsequent breast reconstruction. The treatment of four adolescent females with large breast masses using breast-sparing techniques is discussed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Aesthetic plastic surgery 20 (1996), S. 377-384 
    ISSN: 1432-5241
    Keywords: Mastoplasty ; Vertical scar ; Cutaneous folds ; Cutaneous wrinkles ; Puckering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper presents a series of 54 consecutive cases of vertical mastoplasty carried out over the period February 1994 to April 1995. In 30 cases breast reduction was performed, in 19 pure mastopexy, and in the remaining 5, a mastopexy-breast augmentation with a silicon gel prosthesis was carried out. The parameters used for analyzing the persistence of vertical scarring were: inframammary cutaneous folds, wrinkling of the skin, and puckering at 1, 3, and 6 months during the postoperative period. An attempt has been made to establish how the vertical scar has evolved over this period. The study done by age groups as well as the study of the breast's cutaneoglandular characteristics provides data as to with which morphotype and worst results were obtained.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Aesthetic plastic surgery 20 (1996), S. 391-397 
    ISSN: 1432-5241
    Keywords: Breast reduction ; Breast tumors ; Breast tumor screening ; Mammography ; Ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We conducted a retrospective study to evaluate the diagnosability of breast tumors after breast reductions as this is a frequent surgical procedure. The data should shed light on the hypothesis that routine screening methods concerning the diagnosis of breast tumors prove more difficult after breast operations. All women who had undergone breast reduction at our department between January 1989 and December 1994 were examined. During this period we counted 166 patients; the majority of them (n = 144) had undergone a bilateral breast reduction and the rest of them (n = 22) a unilateral breast reduction for various reasons. After the operation, all patients were checked in standardized intervals. Those who developed any kind of breast mass (n = 6) were recorded and examined by ultrasound and mammography, and occasionally by an additional fine-needle biopsy. In case any doubt about the dignity had remained, an excisional biopsy was carried out. In none of our patients was it possible to get a precise diagnosis of an ill-defined mass with ultrasound. With mammography, some of the existing masses, which were really scars, mimicked different kinds of tumors, and once a carcinoma was initially interpreted as scar tissue with oil cysts. The diagnosis of breast masses after breast reductions with routinely used screening methods has proved to be more difficult as breast reductions lead to architectural alterations of the remaining breast parenchyma. Such alterations can and should be documented shortly after the operation so that later occurring tumors are distinguished more easily. Therefore, a basic mammography 3 months after each breast reduction has to be claimed in order to facilitate further breast tumor diagnosis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    ISSN: 1619-7089
    Keywords: Positron emission tomography ; Fluorine-18 fluoro-2-deoxy-d-glucose ; Breast tumors ; Axillary lymph nodes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The noninvasive staging of axillary lymph nodes for metastases is investigated in patients with breast cancer prior to surgery by positron emission tomography (PET) with fluorine- l8-fluoro-2-deoxy-d-glucose (18F-FDG). In 124 patients with newly diagnosed breast cancer, whole-body PET was performed to determine the average differential uptake ratio (DUR) of18F-FDG in the axillary lymph nodes. Results were correlated with the number of the dissected lymph nodes, size of the primary tumor, tumor type, tumor grade, estrogen and progesterone receptors, DNA ploidy, and the proportion of cells in the synthetic phase of the cell cycle (S-phase). In this prospective study of 124 patients with breast carcinoma, PET correctly categorized all 44 tumor-positive axillary lymph nodes, a sensitivity of 100%. Sixty tumor-negative axillary lymph nodes were negative by PET and 20 tumor-negative axillary lymph nodes were positive by PET. No false-negative PET findings were encountered. A weak correlation was found between DUR and tumor size as well as between DUR and the S-phase of the tumor. In patients with breast carcinoma,18F-FDG PET can be of value in evaluating axillary lymph nodes for metastatic involvement prior to surgery. It is of particular importance that no false-negative PET findings were encountered, and axillary lymph node dissection might not be necessary in patients without axillary uptake by PET. The DUR of the positive axillary lymph nodes seems to bear a relationship with some of the purported prognostic parameters of the primary tumor.
    Type of Medium: Electronic Resource
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