ISSN:
1432-0878
Keywords:
Pituitary glands
;
Anterior pituitary hormones
;
Pars tuberalis
;
Posterior pituitary glands
;
Immunohistochemistry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Pituitary glands were examined using reference staining (hematoxylin and eosin, periodic acid-Schiff and alcian blue) and the peroxidase-labeled antibody method, for 1) “invading” anterior cells in the posterior lobe, 2) intermediate colloid forming follicles, and 3) pars tuberalis cells. The results showed: 1) that the majority of cases possessed “invading” anterior cells of various amount. Most of these cells were positive for ACTH1–18, ACTH17–39 and β-MSH. However, on a few occasions, scattered GH, PRL, FSHα, FSHβ, LHβ and even TSHβ cells were also present. 2) Colloid forming follicular cells were mostly ACTH cells, but also contained occasional other hormone-secreting cells. Hormone negative cells were correlated with salivary type epithelium. Well established acinic type salivary glands and ciliated epithelium were negative for any hormones immunohistochemically. 3) Pars tuberalis cells were predominantly gonadotrophs but also included TSHβ and ACTH cells. Some cells appeared to contain both FSHβ and LHβ. When these cells underwent squamous metaplasia, they seemed to lose their hormone secreting activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00236170
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