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  • 1985-1989  (4)
  • 1975-1979
  • 1960-1964  (3)
  • 1880-1889
  • 1987  (4)
  • 1963  (3)
  • 1881
  • Biosynthesis
  • 1
    Electronic Resource
    Electronic Resource
    Glycoconjugate biosynthesis in human epidermis (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 251-256 
    Details
    ISSN: 1432-069X
    Keywords: Glycoproteins ; Glycosaminoglycans ; Epidermis ; Biosynthesis ; Electrophoresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Epidermal glycoconjugates synthesized by skin slices in media containing radiolabelled sugars were analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis. A large proportion of the epidermal glycoconjugates were soluble in 10% (w/v) trichloroacetic acid. In addition to glycolipids and glycosaminoglycans, the acid-soluble fraction contained glycoproteins, a group of which (mol. wt. 70,000–160,000) were highly glycosylated and particularly rich in fucose. Analysis of the glycosaminoglycans by cellulose acetate electrophoresis combined with specific enzymic and nitrous acid degradation studies revealed that hyaluronic acid (73%) and heparan sulphate (18%) were the main components.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00417324
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  • 2
    Electronic Resource
    Electronic Resource
    Cardenolide biosynthesis in chrysomelid beetles (1987)
    Springer
    Cellular and molecular life sciences 43 (1987), S. 460-462 
    Details
    ISSN: 1420-9071
    Keywords: Biosynthesis ; cardenolides ; Coleoptera ; chrysomelid beetles ; [23-14C]-cholesterol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Labeling experiments have shown that the chrysomelid beetleChrysolina coerulans is able to biosynthesize its own defensive cardenolides from cholesterol, via a pathway involving a C21 intermediate, as in plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01940455
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immuno-electron microscopy of formation, degradation and exocytosis of the ovulation neurohormone in Lymnaea stagnalis (1987)
    Springer
    Cell & tissue research 250 (1987), S. 441-448 
    Details
    ISSN: 1432-0878
    Keywords: Neuropeptide ; Biosynthesis ; Exocytosis ; Crinophagy ; Ultrastructural immunogold technique ; Lymnaea stagnalis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The cerebral caudodorsal cells (CDC) of the pulmonate snail Lymnaea stagnalis are involved in the control of egg laying and associated behaviour by releasing various peptides. One of these is the ovulation hormone (CDCH). The cellular dynamics of this peptide have been studied using an antiserum raised to a synthetic portion of CDCH comprising the 20–36 amino acid sequence. With the secondary antibody-immunogold technique, specific immunoreactivity was found in all CDC. Rough endoplasmic reticulum and Golgi apparatus showed very little reactivity as did secretory granules that were in the process of being budded off from the Golgi apparatus. However, secretory granules that were being discharged from the Golgi apparatus, were strongly reactive. Secretory granules within lysosomal structures revealed various degrees of immunoreactivity, indicating their graded breakdown. Large electrondense granules, formed by the Golgi apparatus and thought to be involved in intracellular degradation of secretory material, were only slightly reactive. In the axon terminals secretory granules released their contents into the haemolymph by the process of exocytosis. The exteriorized contents were in most cases clearly immunopositive. The possibility has been discussed that CDCH is cleaved from its polypeptide precursor within secretory granules during granule discharge from the Golgi apparatus; subsequently, the mature secretory granules would be transported towards the neurohaemal axon terminals where they release CDCH into the haemolymph. Superfluous secretory material would be degraded by the lysosomal system including the large electron-dense granules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219090
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  • 4
    Electronic Resource
    Electronic Resource
    Defensive chemistry of the flour beetleTribolium brevicornis (LeC): (1987)
    Springer
    Journal of chemical ecology 13 (1987), S. 1707-1723 
    Details
    ISSN: 1573-1561
    Keywords: Biosynthesis ; Coleoptera ; Tenebrionidae ; Tribolium brevicornis ; prostaglandin ; allomones ; synthetase inhibitor ; defensive secretion ; 2′-hydroxy-4′-methoxyacetophenone ; 2′-hydroxy-4′-methoxypropiophenone ; methyl 2,5-dihydroxy-6-methylbenzoate ; methyl 2,5-dihydroxy-6-efhylbenzoate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The defensive secretion ofTribolium brevicornis contains 12 organic components, including quinones, hydroquinones, hydrocarbons, aromatic ketones, and aromatic esters. The two ketones, 2′-hydroxy-4′-methoxyacetophenone and 2′-hydroxy-4′-methoxypropiophenone, and the two esters, methyl 2,5-dihydroxy-6-methylbenzoate and methyl 2,5-dihydroxy-6-ethylbenzoate, represent ca. 0.25% of the biomass of the beetles. Mass spectral and NMR analyses were used to elucidate the structures of all components. The ketones are potent prostaglandin synthetase inhibitors (PSI), and the esters are suspected to be PSI.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00980212
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  • 5
    Electronic Resource
    Electronic Resource
    The Biosynthesis of Alkaloids IIPart I of this review appeared in Angew. Chem. Internet. Edit. 2, 341 (1963). (1963)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 2 (1963), S. 441-458 
    Details
    ISSN: 0570-0833
    Keywords: Biosynthesis ; Alkaloids ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.196304411
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  • 6
    Electronic Resource
    Electronic Resource
    The Biogenesis of Ergot AlkaloidsDedicated to Professor Hans von Euler on the occasion of his 90th birthday (1963)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 2 (1963), S. 243-247 
    Details
    ISSN: 0570-0833
    Keywords: Ergot alkaloids ; Alkaloids ; Biosynthesis ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: In this article the biogenesis of the ergoline ring in lysergic acid derivatives and the clavines is discussed. T·yptophan and mevalonic acid are the precursors. The N-methyl group is supplied by formate or methionine. Concepts and results dealing with the manner in which the compounds are formed are discussed. Finally, the known biogenetic relationships among the ergot alkaloids are discussed in connection with their biogenesis.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.196302431
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  • 7
    Electronic Resource
    Electronic Resource
    The Biosynthesis of Alkaloids IPart II of this review will appear in a subsequent issue of this journal.Dedicated to Professor Dr. Adolf Butenandt on the occasion of his 60th birthday (1963)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 2 (1963), S. 341-357 
    Details
    ISSN: 0570-0833
    Keywords: Biosynthesis ; Alkaloids ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.196303411
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